CAS 921-40-4

(3xi)-5-(acetylamino)-3,5-dideoxy-3-fluoro-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid

Description:

The chemical substance known as (3xi)-5-(acetylamino)-3,5-dideoxy-3-fluoro-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid, with the CAS number 921-40-4, is a derivative of a sugar acid, specifically a nonulosonic acid. This compound features a complex structure characterized by the presence of a fluorine atom, an acetylamino group, and multiple hydroxyl groups, which contribute to its solubility and reactivity. The presence of the dideoxy and fluoro modifications indicates that it may exhibit unique biological properties, potentially influencing its interaction with enzymes or receptors. Such modifications can also affect the compound's stability and its role in biochemical pathways. The stereochemistry of the molecule, indicated by the D-glycero and beta-D-galacto designations, suggests specific spatial arrangements that are crucial for its biological function. Overall, this compound is of interest in biochemical research, particularly in the study of glycoproteins and cell signaling, due to its structural complexity and potential applications in medicinal chemistry.

Formula: C₁₁H₁₈FNO₉

InChI: InChI=1/C11H18FNO9/c1-3(15)13-5-7(18)9(12)11(21,10(19)20)22-8(5)6(17)4(16)2-14/h4-9,14,16-18,21H,2H2,1H3,(H,13,15)(H,19,20)/t4-,5-,6-,7-,8-,9?,11+/m1/s1

N-Acetyl-3-fluoro-neuraminic acid sodium

CAS: 921-40-4

N-Acetyl-3-fluoro-neuraminic acid sodium (AFNA) is an inhibitor that binds to the terminal sialic acid residue of the glycoprotein neuraminidase in influenza viruses, preventing the virus from attaching to cells. AFNA is a fluorinated derivative of mannosamine and is synthesized by reacting an aldolase with sulfur trifluoride. AFNA has been shown to inhibit sialidases and utilising enzymes, which are necessary for viral replication. AFNA also inhibits bacterial sialidases, which are required for the synthesis of cell wall components.

Formula: C₁₁H₁₈FNO₉•Nax₃₂₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 326.25 g/mol

Ref: 3D-MF61553