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CAS 92134-98-0

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Fosphenytoin sodium

Description:
Fosphenytoin sodium is a prodrug of phenytoin, primarily used in the management of seizures, particularly in emergency situations such as status epilepticus. It is a water-soluble compound that facilitates the intravenous administration of phenytoin without the complications associated with the latter's solubility and formulation. Fosphenytoin sodium is characterized by its rapid conversion to phenytoin in the body, allowing for effective therapeutic action. The compound is typically administered as a sodium salt, which enhances its solubility and bioavailability. Its chemical structure includes a phosphate group, which contributes to its solubility profile. Fosphenytoin sodium is generally well-tolerated, but like all medications, it may have side effects, including dizziness, drowsiness, and potential allergic reactions. It is essential to monitor patients for adverse effects and therapeutic efficacy during treatment. Overall, fosphenytoin sodium serves as an important alternative to phenytoin, particularly in acute care settings.
Formula:C16H15N2O6P·2Na
InChI:InChI=1S/C16H15N2O6P.2Na/c19-14-16(12-7-3-1-4-8-12,13-9-5-2-6-10-13)17-15(20)18(14)11-24-25(21,22)23;;/h1-10H,11H2,(H,17,20)(H2,21,22,23);;
InChI key:InChIKey=CKBXTXIAQHEVAB-UHFFFAOYSA-N
SMILES:O=C1C(NC(=O)N1COP(=O)(O)O)(C2=CC=CC=C2)C3=CC=CC=C3.[Na]
Synonyms:
  • 2,4-Imidazolidinedione, 5,5-diphenyl-3-[(phosphonooxy)methyl]-, disodium salt
  • 2,4-Imidazolidinedione, 5,5-diphenyl-3-[(phosphonooxy)methyl]-, sodium salt (1:2)
  • Acc 9653
  • Acc 9653-010
  • Cetebyx
  • Ci 982
  • Disodium (2,5-Dioxo-4,4-Diphenylimidazolidin-1-Yl)Methyl Phosphate
  • Fostoin
  • Pro-Epanutin
  • Fosphenytoin sodium
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