CAS 92136-39-5

N-Boc-propargylamine

Description:

N-Boc-propargylamine is an organic compound characterized by the presence of a propargylamine functional group, which features a terminal alkyne and an amine. The "N-Boc" designation indicates that the amine is protected by a tert-butyloxycarbonyl (Boc) group, a common protecting group in organic synthesis that enhances the stability and solubility of the amine. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and form. It is soluble in organic solvents such as dichloromethane and ethyl acetate, but less soluble in water due to its hydrophobic characteristics. N-Boc-propargylamine is often utilized in organic synthesis, particularly in the preparation of various nitrogen-containing compounds and as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its reactivity is influenced by both the alkyne and amine functionalities, allowing for diverse chemical transformations, including coupling reactions and nucleophilic additions. Safety precautions should be taken when handling this compound, as with many organic chemicals, due to potential irritant properties.

Formula: C₈H₁₃NO₂

InChI: InChI=1/C8H13NO2/c1-5-6-9-7(10)11-8(2,3)4/h1H,6H2,2-4H3,(H,9,10)

SMILES: C#CCN=C(O)OC(C)(C)C

Synonyms:

• N-(tert-Butoxycarbonyl)propargyl amine
• Tert-Butyl Prop-2-Yn-1-Ylcarbamate
• N-Boc-propargyl-1-amine
• N-Boc-Prop-2-ynylamine

N-(tert-Butoxycarbonyl)propargylamine

CAS: 92136-39-5

Formula: C₈H₁₃NO₂

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 155.20

Ref: 3B-B4472

N-Boc-propargylamine, 97%

CAS: 92136-39-5

N-Boc-propargylamine is used to prepare triazolobenzylidene-thiazolopyrimidines. which act as CDC25 phosphatase inhibitors. Further, it is used for the synthesis of beta-glucan polysaccharide analogs. In addition to this, it is involved in the Pauson-Khand (PK) reaction of norbornadiene and N-Boc-pr

Formula: C₈H₁₃NO₂

Purity: 97%

Color and Shape: Solid, Yellow to brown

Molecular weight: 155.20

Ref: 02-H53406

N-Boc-Propargylamine

CAS: 92136-39-5

Formula: C₈H₁₃NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 155.1943

Ref: IN-DA00GRUZ

N-Boc-propargylamine

CAS: 92136-39-5

Formula: C₈H₁₃NO₂

Purity: ≥ 98.0%

Color and Shape: White to tan crystalline powder or solid

Molecular weight: 155.19

Ref: 7W-GX0301

N-Boc-propargylamine

CAS: 92136-39-5

N-Boc-propargylamine

Formula: C₈H₁₃NO₂

Purity: 97%

Color and Shape: pale-yelow solid

Molecular weight: 155.19g/mol

Ref: 54-OR906557

N-Boc-propargylamine

Controlled Product

CAS: 92136-39-5

Applications N-Boc-propargylamine is used in the preparation of triazolobenzylidene-thiazolopyrimidines which act as CDC25 phosphatase inhibitors. Also used in the synthesis of β-glucan polysaccharide analogs.
References Duval, R. et al.: J. Comb. Chem., 11, 947 (2009); Tanaka, H. et al.: Tetrahedron Lett., 53, 4104 (2012);

Formula: C₈H₁₃NO₂

Color and Shape: Neat

Molecular weight: 155.2

Ref: TR-B664260

N-Boc-Prop-2-ynylamine

CAS: 92136-39-5

Formula: C₈H₁₃NO₂

Purity: 98%

Color and Shape: Solid, Chunks or Crystalline Powder

Molecular weight: 155.197

Ref: 10-F040190