CAS 92175-57-0

N-[(2R)-4-(Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-L-alanine

Description:

N-[(2R)-4-(Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-L-alanine, with the CAS number 92175-57-0, is a synthetic amino acid derivative characterized by its complex structure that includes a hydroxyamino group and a dioxo moiety. This compound features a chiral center, which contributes to its potential biological activity and specificity in interactions with biological systems. The presence of the phenylmethyl group suggests that it may exhibit hydrophobic characteristics, influencing its solubility and interaction with lipid membranes. The hydroxyamino group may participate in hydrogen bonding, enhancing its reactivity and potential as a ligand in biochemical pathways. Additionally, the dioxo functional groups can play a role in redox reactions, making this compound of interest in medicinal chemistry and drug design. Its structural complexity and functional groups indicate potential applications in pharmaceuticals, particularly in the development of therapeutics targeting specific biological pathways. However, detailed studies on its pharmacokinetics, toxicity, and efficacy would be necessary to fully understand its potential applications.

Formula: C₁₄H₁₈N₂O₅

InChI: InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/t9-,11+/m0/s1

InChI key: InChIKey=OJCFZTVYDSKXNM-GXSJLCMTSA-N

SMILES: [C@H](CC1=CC=CC=C1)(C(N[C@H](C(O)=O)C)=O)CC(NO)=O

Synonyms:

• <span class="text-smallcaps">L</span>-Alanine, N-[(2R)-4-(hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-
• <span class="text-smallcaps">L</span>-Alanine, N-[4-(hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-, (R)-
• Kelatorphan
• L-alanine, N-[(2R)-4-(hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-
• N-[(2R)-4-(Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-<span class="text-smallcaps">L</span>-alanine
• N-[(2R)-4-(Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-L-alanine
• L-Alanine, N-[4-(hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-, (R)-

Kelatorphan

CAS: 92175-57-0

Kelatorphan is a drug that belongs to the class of nonsteroidal anti-inflammatory drugs. It has been shown to be an inhibitor of the enzyme polymerase chain reaction (PCR) in vitro. Kelatorphan was used as a model system to study the effects of atrial natriuretic peptide (ANP) in inhibiting protein synthesis and cell division. The IC50 for kelatorphan was found to be 0.5 micrograms/mL, which is much lower than its concentration in blood plasma. The IC50 for ANP was found to be between 10-25 micrograms/mL, which is higher than its concentration in blood plasma. Kelatorphan has also been shown to inhibit toll-like receptor 4 (TLR4) and TLR2, which are involved with inflammation and immunity.

Formula: C₁₄H₁₈N₂O₅

Purity: Min. 95%

Molecular weight: 294.3 g/mol

Ref: 3D-SDA17557

Kelatorphan

CAS: 92175-57-0

Kelatorphan is an enkephalin degrading enzyme full inhibitor.

Formula: C₁₄H₁₈N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 294.3

Ref: TM-T15652