2'-TBDMS-5-Me-rU, also known as 2'-O-tert-butyldimethylsilyl-5-methyluridine, is a modified nucleoside that features a tert-butyldimethylsilyl (TBDMS) protecting group at the 2' position and a methyl group at the 5 position of the uridine base. This modification enhances the stability and solubility of the nucleoside, making it useful in various biochemical applications, particularly in the synthesis of RNA and oligonucleotides. The TBDMS group serves as a protective moiety that can be removed under specific conditions, allowing for selective deprotection during synthetic processes. The presence of the methyl group at the 5 position can influence the nucleoside's base pairing properties and its overall reactivity. This compound is often utilized in research settings, particularly in studies involving RNA structure and function, as well as in the development of therapeutic oligonucleotides. Its unique structural features contribute to its utility in nucleic acid chemistry and molecular biology.

2'-TBDMS-5-Me-rU

922508-26-7: 2'-TBDMS-5-Me-rU, also known as 2'-O-tert-butyldimethylsilyl-5-methyluridine, is a modified nucleoside that features a tert-butyldimethylsilyl (TBDMS) protecting group at the 2' position and a methyl group at the 5 position of the uridine base. This modification enhances the stability and solubility of the nucleoside, making it useful in various biochemical applications, particularly in the synthesis of RNA and oligonucleotides. The TBDMS group serves as a protective moiety that can be removed under specific conditions, allowing for selective deprotection during synthetic processes. The presence of the methyl group at the 5 position can influence the nucleoside's base pairing properties and its overall reactivity. This compound is often utilized in research settings, particularly in studies involving RNA structure and function, as well as in the development of therapeutic oligonucleotides. Its unique structural features contribute to its utility in nucleic acid chemistry and molecular biology.

<p>2'-O-tert-Butyldimethylsilyl-5-methyluridine is a monophosphate of 5-methyluridine. It is an analog of uracil and has been used as an antiviral agent, as well as for the prevention of colorectal cancer. 2'-O-tert-Butyldimethylsilyl-5-methyluridine is also known to be a potent activator of the ribonucleotide reductase enzyme, which may contribute to its anticancer effects. This compound has a high purity and quality, making it easy to use in various applications.</p>

CAS 922508-26-7

2'-TBDMS-5-Me-rU

2'-TBDMS-5-Me-rU

Ref: IN-DA0060QU

2'-O-tert-Butyldimethylsilyl-5-methyluridine

Ref: 3D-NT57546