CAS 922731-01-9

OMeprazole-d3

Description:

Omeprazole-d3 is a deuterated form of the proton pump inhibitor omeprazole, which is primarily used to treat gastroesophageal reflux disease (GERD) and other conditions related to excessive stomach acid production. The "d3" designation indicates that three hydrogen atoms in the molecule have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the substance's stability and allow for more precise tracking in pharmacokinetic studies. Omeprazole-d3 retains the core structure and pharmacological properties of omeprazole, functioning by inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, thereby reducing gastric acid secretion. Its chemical formula reflects the presence of deuterium, and it typically appears as a white to off-white crystalline powder. The substance is utilized in research settings, particularly in studies involving drug metabolism and pharmacodynamics, due to its isotopic labeling, which aids in differentiating it from non-deuterated compounds in analytical techniques such as mass spectrometry.

Formula: C₁₇H₁₆D₃N₃O₃S

Synonyms:

• Omeprazole (benzimidazole 5-trideuteriomethoxy)
• Omeprazole-(5-methoxy-d3)
• 1H-Benzimidazole,6-(methoxy-d3)-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
• H 16868 D3
• 5-Methoxy-d3-2-{[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole
• [2H3]-Omeprazole

Omeprazole-d3 (Methyl-d3 on Benzene)

CAS: 922731-01-9

Formula: C₁₇H₁₆D₃N₃O₃S

Molecular weight: 348.44

Ref: 4Z-O-02191

Omeprazole-d3

CAS: 922731-01-9

Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)

Formula: C₁₇H₁₉N₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 348.44

Ref: TM-T12308

Omeprazole-d3

Controlled Product

CAS: 922731-01-9

Applications Labelled Omeprazole, which binds covalently to proton pump, it inhibits gastric secretion. Used as an anttiulcerative.
References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)

Formula: C₁₇₂H₃H₁₆N₃O₃S

Color and Shape: Neat

Molecular weight: 348.43

Ref: TR-O635002

Omeprazole (benzimidazole 5-trideuteriomethoxy)

CAS: 922731-01-9

Formula: C₁₇H₁₆D₃N₃O₃S

Purity: 98.99%

Color and Shape: Solid

Molecular weight: 348.4345

Ref: IN-DA00GU9A