CAS 923032-37-5: Refametinib

Formula: C₁₉H₂₀F₃IN₂O₅S

InChI: InChI=1S/C19H20F3IN2O5S/c1-30-15-7-13(21)16(22)18(24-14-3-2-10(23)6-12(14)20)17(15)25-31(28,29)19(4-5-19)8-11(27)9-26/h2-3,6-7,11,24-27H,4-5,8-9H2,1H3/t11-/m0/s1

InChI key: InChIKey=RDSACQWTXKSHJT-NSHDSACASA-N

SMILES: O=S(=O)(NC=1C(OC)=CC(F)=C(F)C1NC2=CC=C(I)C=C2F)C3(CC3)CC(O)CO

Synonyms:

• N-[3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl]-1-[(2S)-2,3-dihydroxypropyl]cyclopropanesulfonamide
• BAY 8697661
• RDEA 119
• Cyclopropanesulfonamide, N-[3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl]-1-[(2S)-2,3-dihydroxypropyl]-
• BAY 869766

RDEA119

CAS: 923032-37-5

• Formula: C₁₉H₂₀F₃IN₂O₅S
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 572.3372

Refametinib

CAS: 923032-37-5

• Purity: ≥98%
• Molecular weight: 572.34g/mol

Refametinib

CAS: 923032-37-5

• Molecular weight: 572.34g/mol

Refametinib

CAS: 923032-37-5

Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 …

• Formula: C₁₉H₂₀F₃IN₂O₅S
• Purity: 100% - 99.84%
• Color and Shape: Solid
• Molecular weight: 572.34

Refametinib

CAS: 923032-37-5

Inhibitor of MEK1 and MEK2 kinases

• Formula: C₁₉H₂₀F₃IN₂O₅S
• Purity: Min. 95%
• Molecular weight: 572.34 g/mol