CAS 923288-90-8
:Nilotinib hcl monohydrate
Description:
Nilotinib hydrochloride monohydrate is a small molecule tyrosine kinase inhibitor primarily used in the treatment of chronic myeloid leukemia (CML). It is characterized by its ability to selectively inhibit the BCR-ABL fusion protein, which is responsible for the proliferation of cancer cells in CML. The compound is typically presented as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in a clinical setting. Its chemical formula includes a hydrochloride salt and a monohydrate form, indicating the presence of one water molecule per formula unit. Nilotinib exhibits a high affinity for the ATP-binding site of the BCR-ABL protein, which enhances its efficacy compared to other treatments. The pharmacokinetics of nilotinib show a relatively long half-life, allowing for once or twice daily dosing. Common side effects may include nausea, fatigue, and hematological abnormalities, necessitating regular monitoring of blood counts during treatment. Overall, nilotinib hydrochloride monohydrate represents a significant advancement in targeted cancer therapy.
Formula:C28H22F3N7OHClH2O
Synonyms:- Nilotinib hydrochloride monohydrate
- Nilotinib monohydrochloride monohydrate
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Found 12 products.
Nilotinib
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFormula:C28H22F3N7OHClH2OColor and Shape:Light Yellow PowderMolecular weight:529.183794-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}benzamide hydrochloride hydrate
CAS:Formula:C28H25ClF3N7O2Purity:%Color and Shape:SolidMolecular weight:583.9920Nilotinib monohydrochloride monohydrate
CAS:Nilotinib monohydrochloride monohydratePurity:≥98%Molecular weight:583.99g/molNilotinib hydrochloride monohydrate
CAS:Nilotinib hydrochloride monohydratePurity:98%Molecular weight:584g/molNilotinib Hydrochloride Monohydrate
CAS:Formula:C28H22F3N7O·ClH·H2OColor and Shape:NeatMolecular weight:583.99Nilotinib monohydrochloride monohydrate
CAS:<p>Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosine</p>Formula:C28H22F3N7O·HCl·H2OPurity:99.93%Color and Shape:SolidMolecular weight:583.99Nilotinib Monohydrochloride Monohydrate
CAS:Controlled ProductFormula:C28H22F3N7O·ClH·H2OColor and Shape:NeatMolecular weight:583.99Nilotinib HCl monohydrate - Bio-X ™
CAS:<p>Nilotinib is a kinase inhibitor that is used for the treatment of Chronic Myeloid Leukemia (CML). This drug is also used for the treatment of CML that is resistant to imatinib. Nilotinib inhibits the tyrosine kinase activity of the BCR-ABL protein. It also inhibits PDGFR and c-kit.</p>Formula:C28H22F3N7O•HCl•H2OPurity:Min. 95%Color and Shape:PowderMolecular weight:583.99 g/molNilotinib HCl monohydrate
CAS:<p>Bcr-Abl inhibitor; also inhibits PDGFR and c-kit; antineoplastic</p>Formula:C28H22F3N7O·HCl·H2OPurity:Min. 95%Color and Shape:White PowderMolecular weight:583.99 g/molNilotinib Hydrochloride Monohydrate
CAS:Formula:C28H22F3N7OHClH2OMolecular weight:529.53 : 36.46 : 18.02
![4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(3-pyridinyl)-2-pyrimid…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003A7S.jpg&w=3840&q=75)
