CAS 923932-05-2

Sesamol-d2

Controlled Product

CAS: 923932-05-2

Applications Sesamol-d2 is the isotope labelled analog of Sesamol (S280600), which is a natural component of sesame oil with antioxidant activity. Sesamol has potential protective effects against free radicals as well as some antifungal activity. Sesamol can also be used as an intermediate in the preparation of antidepressants such as Paroxetine (P205750).
References Kim, J.Y. et al.: J. Agric. Food Chem., 51, 3460 (2003); Toshiko, O.: New Food Indust., 33, 1 (1991); Wynn, J.P. et al.: Lipids, 32, 605 (1997);

Formula: C₇D₂H₄O₃

Color and Shape: Neat

Molecular weight: 140.133

Ref: TR-S280602

Sesamol-d2

Controlled Product

CAS: 923932-05-2

Sesamol-d2 is an oral prodrug that belongs to the class of morpholinos. It acts as a mitochondrial DNA ligase inhibitor, preventing the repair of oxidative damage to DNA. Sesamol-d2 has been shown to reduce fungal biomass and inhibit RNA concentration in a reaction solution containing adenine and tenofovir alafenamide hemifumarate. It also inhibits base-excision repair, leading to increased levels of oxidative DNA damage. Furthermore, Sesamol-d2 has been found to have plasma-level effects on various impurities, as demonstrated through molecular docking studies.

Formula: C₇H₆O₃

Purity: Min. 95%

Molecular weight: 140.13 g/mol

Ref: 3D-YLB93205