CAS 923981-14-0

Centanafadine HCl

Description:

Centanafadine HCl, with the CAS number 923981-14-0, is a novel chemical compound primarily investigated for its potential use in treating attention-deficit hyperactivity disorder (ADHD). It is classified as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI), which means it works by modulating the levels of these neurotransmitters in the brain, thereby enhancing focus and attention. The compound exhibits a unique mechanism of action compared to traditional stimulants, potentially offering a different side effect profile. Centanafadine HCl is typically presented as a hydrochloride salt, which enhances its solubility and stability. In terms of physical properties, it is usually a white to off-white crystalline powder. The pharmacokinetics of centanafadine suggest a moderate half-life, allowing for once-daily dosing in clinical settings. Ongoing research aims to further elucidate its efficacy, safety, and tolerability in various populations, particularly in children and adolescents diagnosed with ADHD. As with any pharmaceutical agent, comprehensive clinical trials are essential to establish its therapeutic potential and regulatory approval.

Formula: C₁₅H₁₆ClN

Synonyms:

• Centanafadine hydrochloride (EB-1020 (hydrochloride))
• Centafadine hydrochloride
• CTN SR
• Centanafadine hydrochloride (Synonyms: EB-1020 (hydrochloride))
• Centanafadine,SLC6A3,5-HTT,EB 1020,Centanafadine hydrochloride,Dopamine Transporter,SLC6A4,Beta Receptor,DAT,EB-1020,inhibit,SERT,Serotonin Transporter,EB1020,Adrenergic Receptor,Inhibitor
• EB-1020 hydrochloride
• (1R,5S)-(+)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane hydrochloride
• EB-1020 SR
• Centanafadine HCl

Centanafadine hydrochloride

CAS: 923981-14-0

Centanafadine HCl is a NE/DA reuptake inhibitor, also affects serotonin (IC50: NE 6 nM, DA 38 nM, serotonin 83 nM).

Formula: C₁₅H₁₆ClN

Purity: 99.65%

Color and Shape: Solid

Molecular weight: 245.75

Ref: TM-T10758L

Centanafadine hydrochloride

CAS: 923981-14-0

Centanafadine hydrochloride

Purity: ≥98%

Molecular weight: 245.75g/mol

Ref: 54-BUP11993

Centanafadine-d7 Hydrochloride

Controlled Product

CAS: 923981-14-0, 924012-43-1

Formula: C₁₅H₈D₇N•HCl

Color and Shape: Neat

Molecular weight: 252.79

Ref: TR-C256622

Centanafadine Hydrochloride

Controlled Product

CAS: 923981-14-0

Applications Centanafadine Hydrochloride is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) used as a treatment for attention deficit hyperactivity disorder (ADHD) that is in phase II clinical trials.

Formula: C₁₅H₁₅N·ClH

Color and Shape: Neat

Molecular weight: 245.747

Ref: TR-C256620