CAS 924-44-7

Ethyl glyoxylate

Description:

Ethyl glyoxylate, with the CAS number 924-44-7, is an organic compound classified as an α-hydroxy carbonyl compound. It is characterized by its colorless to pale yellow liquid form and has a sweet, fruity odor. Ethyl glyoxylate is soluble in water and organic solvents, making it versatile for various applications. The compound features a carbonyl group (C=O) adjacent to a hydroxyl group (–OH), which contributes to its reactivity, particularly in condensation reactions and as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It can undergo oxidation to form glyoxylic acid or participate in Michael addition reactions due to its electrophilic nature. Ethyl glyoxylate is also used in the production of flavoring agents and fragrances, as well as in the synthesis of polymers and other fine chemicals. However, it should be handled with care, as it may pose health risks upon exposure, including irritation to the skin and respiratory system. Proper safety measures should be observed when working with this compound.

Formula: C₄H₆O₃

InChI: InChI=1S/C4H6O3/c1-2-7-4(6)3-5/h3H,2H2,1H3

InChI key: InChIKey=DBPFRRFGLYGEJI-UHFFFAOYSA-N

SMILES: C(OCC)(C=O)=O

Synonyms:

• Acetic acid, 2-oxo-, ethyl ester
• Acetic acid, oxo-, ethyl ester
• Ethyl 2-Oxoacetate
• Ethyl glyoxylate
• Ethyl oxoacetate
• Ethylglyoxylat
• Formyl ethoxy ketone
• Glioxilato De Etilo
• Glyoxalic acid ethyl ester
• Glyoxylate d'ethyle
• Glyoxylic acid ethyl ester
• Glyoxylsaureethylester
• Nsc 49206

Ethyl Glyoxylate Polymer form (47% in Toluene)

CAS: 924-44-7

Formula: (CH₃CH₂OCOCHO)n

Color and Shape: Colorless to Almost colorlessclear liquid

Ref: 3B-G0264

Ethyl glyoxylate, ca 50% soln. in toluene

CAS: 924-44-7

Ethyl glyoxylate is widely used as an intermediate in the synthesis of pharmaceuticals (high reactivity of aldehyde function). It is used in the synthesis of a biodegradable polymer, poly(ethyl glyoxylate). It is actively involved in the Friedel-Crafts alkylation reactions with thiophenes to give th

Formula: C₄H₆O₃

Color and Shape: Solution, Clear colorless to pale yellow

Molecular weight: 102.09

Ref: 02-L19207

Ethyl glyoxylate, 50% solution in toluene

CAS: 924-44-7

Formula: OHCCO₂CH₂CH₃

Purity: ≥ 97.0%

Color and Shape: Colourless to pale yellow liquid

Molecular weight: 102.09

Ref: 7W-GK3846

Ethyl oxoacetate, 50% solution in toluene

CAS: 924-44-7

Ethyl oxoacetate, 50% solution in toluene

Formula: C₄H₆O₃

Purity: tech

Color and Shape: clear. almost colourless liquid

Molecular weight: 102.08864g/mol

Ref: 54-OR59968

Ethyl 2-oxoacetate in 50% Toluene (polymerised)

CAS: 924-44-7

Formula: C₄H₆O₃

Purity: 97.0%

Color and Shape: Liquid, Oil

Molecular weight: 102.089

Ref: 10-F079534

Ethyl glyoxalate - 50% in toluene

CAS: 924-44-7

Ethyl glyoxalate is a fatty acid that has a hydroxyl group on the second carbon. It is used in palladium-catalyzed coupling reactions to form covalent linkages. This compound has been shown to be an effective antimicrobial agent against amine and ester hydrochloride, as well as being active against several bacteria strains. The asymmetric synthesis of this compound is achieved by reacting diethyl ketomalonate with acetaldehyde in the presence of catalytic quantities of palladium, which leads to formation of two different enantiomers. The reaction mechanism has been elucidated, revealing that the reaction proceeds via a carbonyl addition followed by nucleophilic attack on the ketone oxygen atom. Structural analysis demonstrates that the product formed can be either syn or anti depending on the orientation of reactants during reaction.

Formula: C₄H₆O₃

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 102.09 g/mol

Ref: 3D-FE29894

Ethyl Glyoxylate-13C4

Controlled Product

CAS: 924-44-7

Applications Ethyl Glyoxylate-13C4 is an isotope labelled analog of Ethyl Glyoxylate. Ethyl Glyoxylate is used as a reagent in the synthesis of a new class of cinnamyl-triazole compounds which can be used as selective inhibitors of human aromatase (cytochrome P 450 19A1).
References McNulty, J., et al.: Bioorg. Med. Chem. Lett., 24, 4586 (2014)

Formula: C₄H₆O₃

Color and Shape: Neat

Molecular weight: 106.059

Ref: TR-E918552