CAS 92440-76-1

2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(3H)-pyrimidinone

Description:

2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(3H)-pyrimidinone is a chemical compound characterized by its pyrimidinone core, which features an amino group and a phenylmethyl substituent with three methoxy groups on the phenyl ring. This structure contributes to its potential biological activity, as the presence of multiple methoxy groups can enhance lipophilicity and influence interactions with biological targets. The compound is likely to exhibit properties typical of pyrimidinones, such as being a weak base due to the amino group, and it may participate in hydrogen bonding due to the presence of both the amino and carbonyl functionalities. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, as compounds with similar frameworks have been explored for various therapeutic effects. However, specific data regarding its solubility, stability, and reactivity would require empirical investigation. Overall, this compound represents a class of organic molecules that may have significant implications in drug design and development.

Formula: C₁₄H₁₇N₃O₄

InChI: InChI=1S/C14H17N3O4/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-16-14(15)17-13(9)18/h5-7H,4H2,1-3H3,(H3,15,16,17,18)

InChI key: InChIKey=ZKFZTBRMADDRMK-UHFFFAOYSA-N

SMILES: C(C1=CC(OC)=C(OC)C(OC)=C1)C=2C(=O)NC(N)=NC2

Synonyms:

• 2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-1H-pyrimidin-6-one
• 2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(3H)-pyrimidinone
• 2-amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-4(3H)-one
• 4(1H)-Pyrimidinone, 2-amino-5-[(3,4,5-trimethoxyphenyl)methyl]-
• 4(3H)-Pyrimidinone, 2-amino-5-[(3,4,5-trimethoxyphenyl)methyl]-
• 4-Pyrimidinol, 2-amino-5-(3,4,5-trimethoxybenzyl)-
• 2-Amino-5-((3,4,5-trimethoxyphenyl)methyl)-1H-pyrimidin-4-one

Trimethoprim EP Impurity D

CAS: 92440-76-1

Formula: C₁₄H₁₇N₃O₄

Molecular weight: 291.31

Ref: ST-EA-CP-T8004

Trimethoprim 4-ol (2-amino-5-(3,4,5-trimethoxybenzyl) pyrimidin-4-ol)

CAS: 92440-76-1

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₁₄H₁₇N₃O₄

Color and Shape: Off-White Fine Powder

Molecular weight: 291.12191

Ref: 45-1A05950

Trimethoprim EP Impurity D

CAS: 92440-76-1

Formula: C₁₄H₁₇N₃O₄

Color and Shape: Off-White Solid

Molecular weight: 291.31

Ref: 4Z-T-703

2-Amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-4-ol

Controlled Product

CAS: 92440-76-1

Formula: C₁₄H₁₇N₃O₄

Color and Shape: Neat

Molecular weight: 291.30

Ref: 86-MM0093.04

2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(1H)-pyrimidinone

Controlled Product

CAS: 92440-76-1

Applications Degradation product/impurity of trimethoprim (T795615).
References Roth, B., et al.: J., Med. Pharm. Chem., 5, 1103 (1962), Bergh, J., et al.: J. Pharm. Sci., 78, 348 (1989),

Formula: C₁₄H₁₇N₃O₄

Color and Shape: Neat

Molecular weight: 291.30

Ref: TR-A630830