CAS 924663-37-6

Rebeprazole sulfone N-oxide

Description:

Rebeprazole sulfone N-oxide, identified by its CAS number 924663-37-6, is a chemical compound that belongs to the class of proton pump inhibitors (PPIs). It is a derivative of rebeprazole, which is used primarily for the treatment of gastroesophageal reflux disease (GERD) and other conditions related to excessive stomach acid production. The sulfone N-oxide modification enhances its pharmacological properties, potentially improving its efficacy and stability. This compound typically exhibits characteristics such as high solubility in polar solvents, which is advantageous for its bioavailability. Additionally, it may possess a specific molecular structure that contributes to its mechanism of action, inhibiting the proton pump in gastric parietal cells, thereby reducing acid secretion. The safety profile and side effects of rebeprazole sulfone N-oxide are generally consistent with those of other PPIs, including gastrointestinal disturbances and potential interactions with other medications. As with any pharmaceutical compound, its use should be guided by clinical evidence and regulatory approval.

Formula: C₁₈H₂₁N₃O₅S

InChI: InChI=1/C18H21N3O5S/c1-13-16(21(22)9-8-17(13)26-11-5-10-25-2)12-27(23,24)18-19-14-6-3-4-7-15(14)20-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,19,20)

SMILES: Cc1c(CS(=O)(=O)c2nc3ccccc3[nH]2)n(=O)ccc1OCCCOC

Synonyms:

• 2-[[[4-(3-Methoxypropoxy)-3-methyl-1-oxido-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole
• 2-({[4-(3-methoxypropoxy)-3-methyl-1-oxidopyridin-2-yl]methyl}sulfonyl)-1H-benzimidazole

Rabeprazole EP Impurity I

CAS: 924663-37-6

Formula: C₁₈H₂₁N₃O₅S

Color and Shape: White To Off-White Solid

Molecular weight: 391.44

Ref: 4Z-R-208

Rabeprazole Sulphone N-Oxide

Controlled Product

CAS: 924663-37-6

Formula: C₁₈H₂₁N₃O₅S

Color and Shape: Neat

Molecular weight: 391.44

Ref: 86-MM0618.05

Rabeprazole EP Impurity I

CAS: 924663-37-6

Formula: C₁₈H₂₁N₃O₅S

Molecular weight: 391.44

Ref: ST-EA-CP-R5009

Rabeprazole Sulfone N-Oxide

Controlled Product

CAS: 924663-37-6

Impurity Rabeprazole EP Impurity I
Applications Rabeprazole Sulfone N-Oxide (Rabeprazole EP Impurity I) is a potential impurity of Rabeprazole (R070500) sodium.
References Fujisaki, H., et al.: Biochem. Pharmacol., 42, 321 (1991), Morri, M., et al.: J. Biol. Chem., 268, 21553 (1993)

Formula: C₁₈H₂₁N₃O₅S

Color and Shape: Neat

Molecular weight: 391.44

Ref: TR-R070515