CAS 924811-53-0

BT18

CAS: 924811-53-0

BT18 mimics GDNF, affecting RET receptor tyrosine kinase RetA and GFRα1 function.

Formula: C₃₀H₃₁F₄N₃O₆S

Purity: 99.32%

Color and Shape: Solid

Molecular weight: 637.64

Ref: TM-T13587

BT18

CAS: 924811-53-0

BT18

Purity: ≥98%

Molecular weight: 637.64g/mol

Ref: 54-BUP04545

BT 18

CAS: 924811-53-0

Activator of RET signalling cascade and a derivative of a GFL mimetic compound BT 13. Molecular docking calculations and molecular dynamics simulations were performed in GDNF−GFRα1−RetA complex and showed that BT 18 binds to the allosteric site in GFRα1 as well as RetA surface interfacing GFRα1.

Formula: C₃₀H₃₁F₄N₃O₆S

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 637.64 g/mol

Ref: 3D-BB170419