CAS 924854-60-4

(2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol

Description:

The chemical substance with the name "(2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol" and CAS number "924854-60-4" is a complex organic compound characterized by its unique stereochemistry and structural features. It belongs to the class of isoquinoline derivatives, which are known for their diverse biological activities. The presence of multiple methoxy groups and an isobutyl substituent contributes to its potential pharmacological properties. The stereocenters indicated by the (2S,3R,11bR) configuration suggest that the compound may exhibit specific interactions with biological targets, influencing its efficacy and safety profile. Additionally, the hexahydro structure indicates a saturated ring system, which may affect its solubility and reactivity. Overall, this compound's intricate structure and functional groups make it a subject of interest in medicinal chemistry and drug development, particularly for its potential therapeutic applications.

Formula: C₁₉H₂₉NO₃

InChI: InChI=1S/C19H29NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16-17,21H,5-7,10-11H2,1-4H3/t14-,16-,17+/m1/s1

Synonyms:

• 2H-Benzo[A]Quinolizin-2-Ol, 1,3,4,6,7,11B-Hexahydro-9,10-Dimethoxy-3-(2-Methylpropyl)-, (2S,3R,11Br)-

(+)-β-Dihydrotetrabenazine

CAS: 924854-60-4

Formula: C₁₉H₂₉NO₃

Purity: 95%

Molecular weight: 319.4385

Ref: IN-DA006HUP

Tetrabenazine Metabolite

CAS: 924854-60-4

Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine.

Formula: C₁₉H₂₉NO₃

Purity: 95.07%

Color and Shape: Solid

Molecular weight: 319.44

Ref: TM-T13133

Tetrabenazine Metabolite

CAS: 924854-60-4

Tetrabenazine Metabolite

Purity: ≥95%

Molecular weight: 319.44g/mol

Ref: 54-BUP04687

Tetrabenazine Impurity 40 (2S, 3R, 11bR)

CAS: 924854-60-4

Formula: C₁₉H₂₉NO₃

Molecular weight: 319.45

Ref: 4Z-T-7816

(2S,3R,11bR)-Dihydrotetrabenazine-d7

CAS: 924854-60-4

Formula: C₁₉H₂₂D₇NO₃

Molecular weight: 326.49

Ref: 4Z-T-7849

(+)-β-Dihydrotetrabenazine-13C2D6

Controlled Product

CAS: 924854-60-4

Applications (+)-β-Dihydrotetrabenazine-13C2D6 is the isotope labelled analog of (+)-β-Dihydrotetrabenazine (D453610); a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications.
References Yao, Z., et al.: Eur. J. Med. Chem., 46, 1841 (2011); Rishel, M.J., et al.: J. Org. Chem., 74, 4001 (2009)

Formula: C₂C₁₇D₆H₂₃NO₃

Color and Shape: Neat

Molecular weight: 327.461

Ref: TR-D453612

(+)-β-Dihydrotetrabenazine

Controlled Product

CAS: 924854-60-4

Applications (+)-β-Dihydrotetrabenazine is a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications.
References Yao, Z., et al.: Eur. J. Med. Chem., 46, 1841 (2011); Rishel, M.J., et al.: J. Org. Chem., 74, 4001 (2009)

Formula: C₁₉H₂₉NO₃

Color and Shape: Neat

Molecular weight: 319.438

Ref: TR-D453610

Tetrabenazine Related Impurity 6 (2S,3R,11bR)

CAS: 924854-60-4

Formula: C₁₉H₂₉NO₃

Molecular weight: 319.45

Ref: ST-EA-CP-T104027