CAS 92543-08-3

Cholesterol-2,2,3,4,4,6-d6

Description:

Cholesterol-2,2,3,4,4,6-d6 is a deuterated form of cholesterol, which is a sterol and an essential component of cell membranes in animals. The "d6" designation indicates that six hydrogen atoms in the cholesterol molecule have been replaced with deuterium, a stable isotope of hydrogen. This modification allows for enhanced tracking and analysis in various biochemical studies, particularly in nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. Cholesterol itself plays a crucial role in maintaining membrane fluidity and serves as a precursor for the synthesis of steroid hormones, bile acids, and vitamin D. The presence of deuterium can affect the physical and chemical properties of the molecule, such as its solubility and reactivity, but it retains the fundamental characteristics of cholesterol. Cholesterol-2,2,3,4,4,6-d6 is often used in research to study lipid metabolism, membrane dynamics, and the behavior of cholesterol in biological systems.

Formula: C₂₇H₄₀D₆O

InChI: InChI=1/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19?,21-,22-,23?,24?,25?,26-,27+/m0/s1/i9D,13D2,17D2,21D

Cholesterol-2,2,3,4,4,6-d6

CAS: 92543-08-3

Purity: 98 atom % D

Color and Shape: White Pale-Yellow Solid

Molecular weight: 392.70

Ref: 3U-D3373

Cholesterol-d6

Controlled Product

CAS: 92543-08-3

Stability Hygroscopic
Applications Labelled Cholesterol (C432501). Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.
References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),

Formula: C₂₇₂H₆H₄₀O

Color and Shape: Off White Solid

Molecular weight: 392.69

Ref: TR-C432502

Cholesterol-2,2,3,4,4,6-d6

Controlled Product

CAS: 92543-08-3

Cholesterol-2,2,3,4,4,6-d6 is a chemical compound that is used as a reference standard for cholesterol. It is typically used in the preparation of samples for analysis by nuclear magnetic resonance spectroscopy and other analytical techniques. Cholesterol-2,2,3,4,4,6-d6 has been shown to be an effective inhibitor of influenza virus replication in vitro and in vivo. It also inhibits the replication of a number of other viruses including papillomavirus and herpes simplex virus. The molecule has been shown to bind to the viral membrane system with high affinity and specificity. Cholesterol-2,2,3,4,4,6-d6 also prevents the fusion of influenza virus with host cell membranes by inhibiting the conformational changes required for this process.

Formula: C₂₇D₆H₄₀O

Purity: Min. 95%

Molecular weight: 392.69 g/mol

Ref: 3D-FC29445

Cholesterol-d6

CAS: 92543-08-3

Formula: C₂₇H₄₀D₆O

Color and Shape: Solid

Molecular weight: 392.6905

Ref: IN-DA0064FY