CAS 925432-73-1

3,4,5-Trimethoxy-N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]benzamide

Description:

3,4,5-Trimethoxy-N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]benzamide, with CAS number 925432-73-1, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups. This compound features a benzamide core, substituted with three methoxy groups at the 3, 4, and 5 positions, enhancing its lipophilicity and potentially influencing its biological activity. The presence of a piperazine moiety suggests potential interactions with biological targets, particularly in the central nervous system, due to the piperazine's known pharmacological properties. Additionally, the imidazo[2,1-b]thiazole ring contributes to its heterocyclic nature, which may impart unique reactivity and binding characteristics. The compound's overall structure indicates potential applications in medicinal chemistry, particularly in the development of therapeutic agents. However, specific biological activities, solubility, stability, and toxicity profiles would require further investigation through empirical studies to fully understand its potential uses and effects.

Formula: C₂₆H₂₉N₅O₄S

InChI: InChI=1S/C26H29N5O4S/c1-33-22-12-17(13-23(34-2)24(22)35-3)25(32)28-20-7-5-4-6-19(20)21-15-31-18(16-36-26(31)29-21)14-30-10-8-27-9-11-30/h4-7,12-13,15-16,27H,8-11,14H2,1-3H3,(H,28,32)

InChI key: InChIKey=SBEWVVLMFLTQFE-UHFFFAOYSA-N

SMILES: C(C=1N2C(=NC(=C2)C3=C(NC(=O)C4=CC(OC)=C(OC)C(OC)=C4)C=CC=C3)SC1)N5CCNCC5

Synonyms:

• Benzamide, 3,4,5-trimethoxy-N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-
• 3,4,5-Trimethoxy-N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]benzamide
• 3,4,5-Trimethoxy-N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]benzamide
• 3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide
• 3,4,5-Trimethoxy-n-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide tfa salt
• 3,4,5-triMethoxy-N-(2-(3-(piperazin-1-ylMethyl)iMidazo[2,1-b]thi

3,4,5-Trimethoxy-N-(2-(3-(Piperazin-1-Ylmethyl)Imidazo[2,1-B]Thiazol-6-Yl)Phenyl)Benzamide

CAS: 925432-73-1

3,4,5-Trimethoxy-N-(2-(3-(Piperazin-1-Ylmethyl)Imidazo[2,1-B]Thiazol-6-Yl)Phenyl)Benzamide

Purity: 95%+

Molecular weight: 507.6g/mol

Ref: 54-OR1023968

SRT 1460

CAS: 925432-73-1

SRT 1460

Purity: ≥95%

Molecular weight: 507.6g/mol

Ref: 54-BUP05656

SRT 1460-d9

Controlled Product

CAS: 925432-73-1

Formula: C₂₆H₂₀D₉N₅O₄S

Color and Shape: Neat

Molecular weight: 516.66002

Ref: TR-S684452

SRT 1460 Trifluoroacetic Acid Salt

Controlled Product

CAS: 925432-73-1

Applications SRT 1460 is a drug intended as a small-molecule activator of the sirtuin subtype SIRT1. it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function. References Milne, J., et al.: Nature, 450, 712 (7170); Pacholec, M., et al.: J. BIol. Chem., 285, 8340 (2010); Dai, H., et al.: J. Biol. Chem., 285, 32695 (2010)

Formula: C₂₆H₂₉N₅O₄S•x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 507.6011402

Ref: TR-S684450

SRT 1460

CAS: 925432-73-1

SRT 1460 is a SIRT1 activator.

Formula: C₂₆H₂₉N₅O₄S

Purity: 98.25%

Color and Shape: Solid

Molecular weight: 507.6

Ref: TM-T8346

3,4,5-Trimethoxy-n-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide tfa salt

CAS: 925432-73-1

Formula: C₂₆H₂₉N₅O₄S

Purity: %

Color and Shape: Solid

Molecular weight: 507.6046

Ref: IN-DA0036QQ