CAS 925681-41-0

10-DEBCHydrochloride

CAS: 925681-41-0

Formula: C₂₀H₂₆Cl₂N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 381.3392

Ref: IN-DA01E5UG

10-DEBC hydrochloride

CAS: 925681-41-0

10-Deoxy-10-β-D-arabinofuranosylcytosine (10-DEBC) is a chemotherapeutic drug that is used to treat cancers and degenerative diseases. 10-DEBC is an analog of deoxycytidine and it inhibits the synthesis of DNA by competitively inhibiting the ATP binding cassette transporter, leading to cell death by apoptosis or autophagy. It has been shown to be active against B16 mouse melanoma cells in vitro, as well as atp-binding cassette transporter positive cancer cells in vivo. 10-DEBC also inhibits glycogen synthase kinase 3 (GSK3), which regulates autophagy and apoptotic cell death. 10-DEBC has been shown to induce apoptotic cell death in Caco2 cells, a type of human colon adenocarcinoma cell line.

Formula: C₂₀H₂₅N₂OCl·HCl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 381.34 g/mol

Ref: 3D-FD29857

10-DEBC hydrochloride

CAS: 925681-41-0

10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 μM, is identified as a novel anti-tuberculosis compound [1] [2].

Formula: C₂₀H₂₆Cl₂N₂O

Color and Shape: Solid

Molecular weight: 381.34

Ref: TM-T21778