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CAS 92623-85-3

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Milnacipran

Description:
Milnacipran is a pharmaceutical compound primarily used as an antidepressant and for the treatment of fibromyalgia. It belongs to the class of serotonin-norepinephrine reuptake inhibitors (SNRIs), which function by increasing the levels of serotonin and norepinephrine in the brain, thereby helping to improve mood and alleviate pain. The molecular formula of milnacipran is C15H20N2O, and it has a molecular weight of approximately 244.34 g/mol. The substance is typically administered in its hydrochloride salt form, which enhances its solubility and bioavailability. Milnacipran is characterized by its moderate lipophilicity, allowing it to cross the blood-brain barrier effectively. Common side effects may include nausea, headache, and increased heart rate. It is important to note that milnacipran should be used under medical supervision, as it may interact with other medications and is contraindicated in certain conditions. Overall, milnacipran represents a significant option in the management of depression and chronic pain syndromes.
Formula:C15H22N2O
InChI:InChI=1/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/s2
InChI key:InChIKey=GJJFMKBJSRMPLA-UYWMCZCJNA-N
SMILES:C(N(CC)CC)(=O)[C@]1([C@@H](CN)C1)C2=CC=CC=C2
Synonyms:
  • Milnacipran
  • rel-(1R,2S)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide
  • Midalcipran
  • Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, cis-(±)-
  • Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, (1R,2S)-rel-
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