CAS 92674-40-3
:Methanone, phenyl-5-pyrimidinyl-
Description:
Methanone, phenyl-5-pyrimidinyl- (CAS 92674-40-3) is an organic compound characterized by its structure, which includes a phenyl group and a pyrimidine ring. This compound features a ketone functional group, which is indicative of its classification as a methanone. The presence of the pyrimidine ring suggests potential biological activity, as pyrimidines are often found in various pharmaceuticals and biologically active molecules. The phenyl group contributes to the compound's hydrophobic characteristics, influencing its solubility and interaction with biological systems. Methanone, phenyl-5-pyrimidinyl- may exhibit properties such as moderate stability under standard conditions, but its reactivity can vary based on the presence of substituents and the environment. Additionally, compounds like this can be of interest in medicinal chemistry, particularly in the development of new therapeutic agents. Overall, the unique combination of functional groups in this compound may lead to diverse applications in research and industry, particularly in the fields of drug discovery and development.
Formula:C11H8N2O
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5-Benzoylpyrimidine
CAS:5-Benzoylpyrimidine is an anti-cancer drug that can be used as a monotherapy or in combination with other drugs. It has been shown to have significant activity against cancer cells and tuberculosis. This compound is synthesized by reacting aryl amine with benzoyl chloride in presence of potassium cyanide, followed by hydrolysis of the resulting nitrile. 5-Benzoylpyrimidine has also been shown to inhibit the growth of fungi, such as Candida albicans, Saccharomyces cerevisiae, and Aspergillus niger. The mechanism of action for this drug is not fully understood but may involve inhibition of protein synthesis at the ribosome level or inhibition of mitochondrial function. 5-Benzoylpyrimidine also inhibits the growth of bacteria such as Staphylococcus aureus, Enterobacter aerogenes and Klebsiella pneumoniae.Formula:C11H8N2OPurity:Min. 95%Molecular weight:184.19 g/mol
