CAS 926922-29-4

9-[(1E)-2-(2,6-Dimethylphenyl)ethenyl]-N-[4-(dimethylphosphinyl)phenyl]-9H-purin-6-amine

Description:

The chemical substance known as "9-[(1E)-2-(2,6-Dimethylphenyl)ethenyl]-N-[4-(dimethylphosphinyl)phenyl]-9H-purin-6-amine," with the CAS number 926922-29-4, is a purine derivative characterized by its complex structure that includes a purine core substituted with various functional groups. This compound features a vinyl group attached to a dimethylphenyl moiety, which contributes to its potential biological activity. Additionally, the presence of a dimethylphosphinyl group indicates possible applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. The compound's unique arrangement of atoms and functional groups may influence its solubility, stability, and reactivity, making it of interest for further research in drug design and synthesis. Its specific interactions with biological targets could be explored for therapeutic applications, particularly in oncology or other areas where purine analogs are relevant. Overall, this compound exemplifies the intricate relationship between molecular structure and biological function in the field of chemistry.

Formula: C₂₃H₂₄N₅OP

InChI: InChI=1S/C23H24N5OP/c1-16-6-5-7-17(2)20(16)12-13-28-15-26-21-22(24-14-25-23(21)28)27-18-8-10-19(11-9-18)30(3,4)29/h5-15H,1-4H3,(H,24,25,27)/b13-12+

InChI key: InChIKey=RFSFIDGEFVXSQM-OUKQBFOZSA-N

SMILES: N(C1=C2C(N(/C=C/C3=C(C)C=CC=C3C)C=N2)=NC=N1)C4=CC=C(P(C)(C)=O)C=C4

Synonyms:

• 9H-Purin-6-amine, 9-[(1E)-2-(2,6-dimethylphenyl)ethenyl]-N-[4-(dimethylphosphinyl)phenyl]-
• 9-[(1E)-2-(2,6-Dimethylphenyl)ethenyl]-N-[4-(dimethylphosphinyl)phenyl]-9H-purin-6-amine
• AP 24149

AP 24149

CAS: 926922-29-4

AP 24149, a potent dual inhibitor targeting Src and Abl, exhibits IC50 values of 9.1 nM for Src and 3.6 nM for Abl, respectively.

Formula: C₂₃H₂₄N₅OP

Color and Shape: Solid

Molecular weight: 417.44

Ref: TM-T73345