CAS 927819-64-5

Lisinopril EP Impurity I

CAS: 927819-64-5

Formula: C₃₁H₄₁N₃O₇

Color and Shape: White To Off-White Solid

Molecular weight: 567.68

Ref: 4Z-L-0811

N-(1-Carboxy-3-phenylpropyl)-S-lisinopril (Mixture of diastereomers)

Controlled Product

CAS: 927819-64-5

Applications N-(1-Carboxy-3-phenylpropyl)-S-lisinopril (Mixture of diastereomers) is an impurity of lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor.
References Shinde, V., et. al.: J. Pharm. Biomed. Anal., 43, 381 (2007); Goa, K.L., et al.: Drugs, 52, 564 (1996), Chaturvedi, N., et al.: Lancet, 351, 28 (1998)

Formula: C₃₁H₄₁N₃O₇

Color and Shape: Neat

Molecular weight: 567.67

Ref: TR-C181280

Lisinopril EP Impurity I

CAS: 927819-64-5

Lisinopril EP Impurity I is an impurity of the drug lisinopril. It is a natural product that has been synthesized for use as an analytical standard for pharmacological research and development. Lisinopril EP Impurity I is a synthetic compound that was custom-synthesized from amino acid derivatives and has been used in the manufacture of pharmaceuticals as an impurity standard, including as a high purity HPLC standard. This impurity has been shown to be less toxic than other lisinopril epimerization products, such as lisinopril epimerization product II, which can cause renal toxicity. Lisinopril EP Impurity I also has anti-inflammatory effects and can inhibit LPS-induced production of nitric oxide by macrophages.

Formula: C₃₁H₄₁N₃O₇

Purity: Min. 95%

Molecular weight: 567.7 g/mol

Ref: 3D-IL180422