CAS 92817-10-2

Estra-1,3,5(10)-triene-3,17-diol,16-fluoro-, (16a,17b)-

Description:

Estra-1,3,5(10)-triene-3,17-diol,16-fluoro-, (16a,17b)-, commonly referred to as a synthetic steroid, is characterized by its structural modifications that include a fluorine atom at the 16 position and hydroxyl groups at the 3 and 17 positions. This compound is a derivative of estradiol, a natural estrogen, and is designed to exhibit specific biological activities, particularly in the context of hormone replacement therapy or as a potential therapeutic agent in various medical conditions. The presence of the fluorine atom can enhance the compound's metabolic stability and receptor affinity. Its stereochemistry, indicated by the (16a,17b) notation, suggests a specific three-dimensional arrangement that is crucial for its interaction with estrogen receptors. As a synthetic analog, it may possess unique pharmacokinetic and pharmacodynamic properties compared to its natural counterparts, making it a subject of interest in pharmaceutical research. Safety and efficacy profiles are typically assessed through clinical studies to determine its potential applications in medicine.

Formula: C₁₈H₂₃FO₂

Synonyms:

• 16a-Fluoro-13b-methyl-1,3,5(10)-gonatriene-3,17b-diol
• 16a-Fluoro-17b-estradiol
• 16a-Fluoroestradiol

Estradiol Impurity 10

CAS: 92817-10-2

Formula: C₁₈H₂₃FO₂

Molecular weight: 290.38

Ref: 4Z-E-0990

16α-Fluoroestradiol

Controlled Product

CAS: 92817-10-2

Formula: C₁₈H₂₃FO₂

Color and Shape: Neat

Molecular weight: 290.372

Ref: TR-F928170

(16α,17β)-16-Fluoroestra-1,3,5(10)-triene-3,17-diol

Controlled Product

CAS: 92817-10-2

16alpha,17beta)-16-Fluoroestra-1,3,5(10)-triene-3,17-diol is a potent estrogen receptor modulator that has been shown to inhibit tumor growth in clinical oncology. It acts by binding to the estrogen receptor and blocking its ability to activate gene transcription. This compound can also be used as a pharmaceutical preparation in liquid chromatography. 16alpha,17beta)-16-Fluoroestra-1,3,5(10)-triene-3,17-diol is a liquid at room temperature and can be soluble in organic solvents such as chloroform or acetone. It does not react with hydrochloric acid.

Formula: C₁₈H₂₃FO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 290.37 g/mol

Ref: 3D-FF95572