CAS 92921-24-9
:Sulfo-SMCC sodium
Description:
Sulfo-SMCC sodium, with the CAS number 92921-24-9, is a chemical compound commonly used as a crosslinking agent in bioconjugation and protein chemistry. It is a water-soluble reagent that facilitates the formation of stable covalent bonds between proteins, peptides, and other biomolecules, making it valuable in various applications such as drug development, diagnostics, and the creation of antibody-drug conjugates. The compound features a sulfonate group, which enhances its solubility in aqueous solutions, and a maleimide moiety that selectively reacts with thiol groups in cysteine residues of proteins. This specificity allows for precise modifications of biomolecules, enabling researchers to study protein interactions, stability, and function. Additionally, Sulfo-SMCC sodium is characterized by its mild reaction conditions, making it suitable for use with sensitive biological molecules. Safety precautions should be observed when handling this reagent, as with any chemical, to minimize exposure and ensure proper laboratory practices.
Formula:C16H17N2NaO9S
InChI:InChI=1/C16H18N2O9S.Na/c19-12-5-6-13(20)17(12)8-9-1-3-10(4-2-9)16(23)27-18-14(21)7-11(15(18)22)28(24,25)26;/h5-6,9-11H,1-4,7-8H2,(H,24,25,26);/q;+1/p-1/rC16H17N2NaO9S/c19-28-29(25,26)11-7-14(22)18(15(11)23)27-16(24)10-3-1-9(2-4-10)8-17-12(20)5-6-13(17)21/h5-6,9-11H,1-4,7-8H2
InChI key:InChIKey=VRMVBDHSLMDJAD-UHFFFAOYSA-N
SMILES:O(C(=O)C1CCC(CN2C(=O)C=CC2=O)CC1)N3C(=O)C(S(=O)(=O)O)CC3=O.[Na]
Synonyms:- 3-Pyrrolidinesulfonic acid, 1-[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]oxy]-2,5-dioxo-, sodium salt
- Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester, sodium salt (1:1)
- SMCC, Water-Soluble
- Sulfo-SMCC sodium
- Sulfo-Smcc
- Sulfosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate
- Sulphosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate sodium salt
- [1-[4-[(2,5-Dioxopyrrol-1-Yl)Methyl]Cyclohexanecarbonyl]Oxy-2,5-Dioxo-Pyrrolidin-3-Yl]Sulfonyloxysodium
- SULFO-SMCC SulfosucciniMidyl-trans-4-(n-MaleiMidoMethyl)cyclohexane-1-carboxylate
- Sulfo-N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate
- 3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt
- 4-(N-MaleiMidoMethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysucciniMide ester sodiuM salt, 98+%
- 4-[(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-Cyclohexanecarboxylic acid 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester sodium salt (1:1)
- 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester
- SULFOSUCCINIMIDYL-TRANS-4-(N-MALEIMIDOMETHYL)CYCLOHEXANE-1-CARBOXYLATE
- Sulpho SMCC sodium salt
- SULFO SUCCINIMIDYL-4-(N-MALEIMIDO METHYL) CYCLOHEXANE-1-CARBOXYLATE
- Sulfo-SMCCSulfosucciniMidyl-trans-4-(n-MaleiMidoMethyl)
- Sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarbonyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate
- 3-Sulfo-N-succiniMidyl 4-(N-MaleiMidoMethyl)cyclohexane-1-carboxylate SodiuM Salt
- 4-(N-MALEIMIDOMETHYL)CYCLOHEXANE-1-CARBOXYLIC ACID 3-SULFO-N-HYDROXYSUCCINIMIDE ESTER SODIUM SALT
- Sulfo-N-Succinimidyl-4-(malemidonethyl)cyclohexane-1-carboxylate,sodium salt
- Sulfo-SMCC SodiuM Salt
- 4-(MaleiMidoMethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysucciniMide ester sodiuM salt, 98+%
- 4-[(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)Methyl]cyclohexanecarboxylic Acid 2,5-Dioxo-3-sulfo-1-pyrrolidinyl Ester, SodiuM Salt
- SULFO-N-SUCCINIMIDYL 4-(MALEIMIDOMETHYL)CYCLOHEXANE-1-CARBOXYLATE, SODIUM SALT
- Sulfo-SMCC Crosslinker
- SulfosucciniMidyl 4-(N-MaleiMidoMethyl)cyclohexane-1-carboxylate(Sulfo-SMCC)
- See more synonyms
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Found 9 products.
3-Sulfo-N-succinimidyl 4-(N-Maleimidomethyl)cyclohexane-1-carboxylate Sodium Salt
CAS:Formula:C16H17N2NaO9SPurity:>97.0%(qNMR)Color and Shape:White to Almost white powder to crystalMolecular weight:436.373-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt, 97+%
CAS:<p>3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt is a cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second co</p>Formula:C16H17N2NaO9SPurity:97+%Color and Shape:Off-white to white, SolidMolecular weight:436.37Sulfo-N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate, Sodium Salt
CAS:Formula:C16H17N2NaO9SPurity:98%Color and Shape:SolidMolecular weight:436.3689Sodium 1-((4-((2,5-Dioxo-2,5-Dihydro-1H-Pyrrol-1-yl)Methyl)Cyclohexanecarbonyl)Oxy)-2,5-DioxoPyrrolidine-3-Sulfonate
CAS:Sodium 1-((4-((2,5-Dioxo-2,5-Dihydro-1H-Pyrrol-1-yl)Methyl)Cyclohexanecarbonyl)Oxy)-2,5-DioxoPyrrolidine-3-SulfonatePurity:95%Molecular weight:436.37g/molSulphosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate sodium salt
CAS:<p>Sulphosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate sodium salt</p>Formula:C16H17N2O9S·NaPurity:98% (Typical Value in Batch COA)Color and Shape: white solidMolecular weight:436.37g/molSulfo-SMCC sodium
CAS:<p>Sulfo-SMCC sodium: hetero-bifunctional ADC crosslinker with NHS ester and maleimide for amines and sulfhydryls.</p>Formula:C16H17N2NaO9SPurity:98.07% - 99.9%Color and Shape:SolidMolecular weight:436.37Sulfo-SMCC sodium
CAS:<p>Crosslinker reacting rapidly with primary amines. It is used as a protein crosslinker where it reacts with cysteine to yield specific conjugates. The cyclohexane bridge confers added stability to the maleimide group making it ideal for maleimide activation of proteins. It is soluble in water and many other aqueous buffers although it is less stable then in DMSO or DMF.</p>Formula:C16H17N2O9SNaPurity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:436.37 g/mol
