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CAS 929379-35-1

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6-bromo-2-(trifluoromethyl)quinazolin-4-amine

Description:
6-Bromo-2-(trifluoromethyl)quinazolin-4-amine is a chemical compound characterized by its quinazoline core structure, which is a bicyclic compound containing a fused benzene and pyrimidine ring. The presence of a bromine atom at the 6-position and a trifluoromethyl group at the 2-position significantly influences its chemical properties and reactivity. This compound is typically a solid at room temperature and exhibits moderate solubility in organic solvents, which is common for halogenated and trifluoromethyl-substituted compounds. The trifluoromethyl group enhances lipophilicity and can improve biological activity, making such compounds of interest in medicinal chemistry. Additionally, the amine functional group at the 4-position can participate in hydrogen bonding, affecting its interactions in biological systems. Overall, 6-bromo-2-(trifluoromethyl)quinazolin-4-amine is notable for its potential applications in pharmaceuticals, particularly in the development of targeted therapies due to its unique structural features.
Formula:C9H5BrF3N3
InChI:InChI=1/C9H5BrF3N3/c10-4-1-2-6-5(3-4)7(14)16-8(15-6)9(11,12)13/h1-3H,(H2,14,15,16)
Synonyms:
  • 4-quinazolinamine, 6-bromo-2-(trifluoromethyl)-
  • 6-Bromo-2-(trifluoromethyl)quinazolin-4-amine
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