CAS 92950-39-5

(2alpha,5beta,7beta,10beta,13alpha)-4,7,10-tris(acetyloxy)-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate

Description:

The chemical substance with the name "(2alpha,5beta,7beta,10beta,13alpha)-4,7,10-tris(acetyloxy)-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate" and CAS number "92950-39-5" is a complex organic compound that belongs to the class of taxanes, which are known for their significant biological activity, particularly in cancer treatment. This compound features multiple functional groups, including acetyloxy and benzoylamino moieties, which contribute to its pharmacological properties. The presence of a 9-oxo and epoxide functional group suggests potential reactivity and interaction with biological targets. Its structural complexity, characterized by multiple stereocenters, indicates that it may exhibit stereospecific activity. The compound's solubility, stability, and bioavailability are influenced by its functional groups and overall molecular structure, making it a subject of interest in medicinal chemistry and drug development. Further studies would be necessary to elucidate its specific mechanisms of action and therapeutic potential.

Formula: C₄₉H₅₃NO₁₅

InChI: InChI=1/C49H53NO15/c1-26-33(63-45(58)38(54)37(30-17-11-8-12-18-30)50-43(56)31-19-13-9-14-20-31)24-49(59)42(64-44(57)32-21-15-10-16-22-32)40-47(7,41(55)39(62-28(3)52)36(26)46(49,5)6)34(61-27(2)51)23-35-48(40,25-60-35)65-29(4)53/h8-22,33-35,37-40,42,54,59H,23-25H2,1-7H3,(H,50,56)/t33-,34-,35+,37-,38+,39+,40-,42-,47+,48-,49+/m0/s1

Synonyms:

• benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-4,6,12b-tris(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (alphaR,betaS)-

7-O-Acetylpaclitaxel

CAS: 92950-39-5

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₄₉H₅₃NO₁₅

Color and Shape: White Solid

Molecular weight: 895.34152

Ref: 45-1A08220

ACETYLTAXOL, 7-(P)

CAS: 92950-39-5

Formula: C₄₉H₅₃NO₁₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 895.9428

Ref: IN-DA00GXK3

Paclitaxel EP Impurity L (7-Acetyl Paclitaxel)

CAS: 92950-39-5

Formula: C₄₉H₅₃NO₁₅

Color and Shape: White To Off-White Solid

Molecular weight: 895.96

Ref: 4Z-P-288

7-O-Acetylpaclitaxel

CAS: 92950-39-5

Color and Shape: Neat

Ref: 86-MM1489.15

7-Acetyl Paclitaxel

Controlled Product

CAS: 92950-39-5

Impurity Paclitaxel EP Impurity L
Applications Biologically active Paclitaxel derivative that interacts with tubulin assemblies in the brain. Paclitaxel - Impurity L.
References Burkhart, C., et al.: Canc. Res., 54, 5779 (1994), Ojima, I., et al.: Bioorg. Med. Chem., 11, 2867 (2003),

Formula: C₄₉H₅₃NO₁₅

Color and Shape: Neat

Molecular weight: 895.94

Ref: TR-A187375

Paclitaxel EP Impurity L

CAS: 92950-39-5

Formula: C₄₉H₅₃NO₁₅

Molecular weight: 896

Ref: ST-EA-CP-P36096