CAS 93106-60-6

Enrofloxacin

Description:

Enrofloxacin is a synthetic fluoroquinolone antibiotic primarily used in veterinary medicine to treat bacterial infections in animals. It exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. Enrofloxacin is characterized by its relatively high solubility in water and organic solvents, which facilitates its administration via oral or injectable routes. The compound has a molecular formula that includes a bicyclic structure, contributing to its pharmacological properties. Enrofloxacin is metabolized in the liver to its active form, ciprofloxacin, which also possesses antibacterial activity. While effective, its use is regulated due to concerns about antibiotic resistance and potential effects on human health, particularly in food-producing animals. Safety profiles indicate that it should be used cautiously, considering potential side effects such as gastrointestinal disturbances and effects on cartilage development in young animals. Overall, enrofloxacin remains a critical tool in veterinary medicine, balancing efficacy with responsible usage guidelines.

Formula: C₁₉H₂₂FN₃O₃

InChI: InChI=1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)

InChI key: InChIKey=SPFYMRJSYKOXGV-UHFFFAOYSA-N

SMILES: O=C1C=2C(N(C=C1C(O)=O)C3CC3)=CC(=C(F)C2)N4CCN(CC)CC4

Synonyms:

• 1,4-Dihydro-1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6-Fluoro-4-Oxo-3-Quinoli
• 1-Cyclopropyl-6-fluoro-7-(4-ethyl-1-piperazinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
• 1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
• 1-Cyclopropyl-7-(4-ethyl-piperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
• 1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxoquinoline-3-carboxylic acid
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-
• Alsir
• BAY-Vp 2674
• Bayrocin
• Baytril
• Biofloxavet
• Cfpq
• Enflocyna Sol
• Enrocin
• Enrodac
• Enrofan
• Enroflon
• Enrofloxacine Base Cvp2005
• Enrogil
• Enrovet
• Enroxil
• Fortius
• N'-Ethylciprofloxacin
• N-Ethyl ciprofloxacin
• Pd 160788

Enrofloxacin

CAS: 93106-60-6

Formula: C₁₉H₂₂FN₃O₃

Color and Shape: Neat

Molecular weight: 359.39

Ref: 86-MM0395.00

Enrofloxacin

CAS: 93106-60-6

Impurity Enrofloxacin USP Related Compound Mixture
Applications Fluorinated quinolone antibacterial. Enrofloxacin USP Related Compound Mixture.
References Altreuther, P., et al.: Vet. Med. Rev., 2, 87 (1987),

Formula: C₁₉H₂₂FN₃O₃

Color and Shape: Yellow

Molecular weight: 359.39

Ref: TR-E557800

Enrofloxacin, Antibiotic for Culture Media Use Only

CAS: 93106-60-6

Enrofloxacin is a rapidly bactericidal antibiotic, that inhibits bacterial growth by binding to the 50S ribosomal subunit and blocking protein synthesis, thereby preventing the bacteria from making new proteins. Enrofloxacin also has strong activity against gram-positive bacteria, including Clostridium perfringens which is an anaerobic bacterium that causes food-borne illness. This antibiotic is used for the treatment of acute bacterial infections in humans, such as, skin or soft tissue infections, urinary tract infections (UTIs) and septicemia (bloodstream infection). Enrofloxacin has shown excellent bioavailability with high serum protein binding capacity. Additionally, it has good efficacy against clinical isolates of Escherichia coli and Klebsiella pneumoniae. Enrofloxacin can be used effective in treatments for Pseudomonas aeruginosa and Enterobacter species.

Formula: C₁₉H₂₂FN₃O₃

Purity: Min. 98.5 Area-%

Molecular weight: 359.39 g/mol

Ref: 3D-J-200240

Enrofloxacin

CAS: 93106-60-6

Enrofloxacin is a fluoroquinolone antibiotic with action on bacterial DNA gyrase and topoisomerase IV and is used for treating bacterial infections in animals.

Formula: C₁₉H₂₂FN₃O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 359.39 g/mol

Ref: 3D-AE22674

Enrofloxacin (EFX), 98%

CAS: 93106-60-6

Formula: C₁₉H₂₂FN₃O₃

Purity: min. 98%

Color and Shape: Pale yellow to light yellow, Crystalline powder

Molecular weight: 359.39

Ref: SR-20790

1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

CAS: 93106-60-6

Purity: 98+%

Molecular weight: 359.401001

Ref: 10-F862494