CAS 931417-26-4

ANI-7

CAS: 931417-26-4

ANI-7

Purity: ≥98%

Molecular weight: 263.12g/mol

Ref: 54-BUP13531

ANI-7

CAS: 931417-26-4

ANI-7, an AhR pathway activator, selectively impedes MCF-7 breast cancer cell growth (GI50: 0.56 μM).

Formula: C₁₃H₈Cl₂N₂

Purity: 99.07%

Color and Shape: Solid

Molecular weight: 263.12

Ref: TM-T10325

ANI-7

CAS: 931417-26-4

ANI-7 is a hydrophobic naphthalimide derivative that has been shown to be cytotoxic to cancer cells. It activates the death mediated pathway by binding with the cell surface receptor and then inhibiting the molecule which regulates this process, piperazine. ANI-7 also inhibits DNA synthesis by binding to the acrylonitrile hydroxylase and preventing its activation. This leads to a decrease in cellular DNA content and subsequently cell death. The molecule is also metabolised by cytochrome P450 enzymes, which may explain why it has been found in some cases to be more cytotoxic than other derivatives of naphthalimides.

Formula: C₁₃H₈Cl₂N₂

Purity: Min. 95%

Molecular weight: 263.12 g/mol

Ref: 3D-GMB41726