CAS 932-31-0

2-Methylphenylmagnesium bromide

Description:

2-Methylphenylmagnesium bromide, with the CAS number 932-31-0, is an organomagnesium compound classified as a Grignard reagent. It is characterized by its highly reactive nature, particularly towards electrophiles, due to the presence of the carbon-magnesium bond. This compound features a phenyl ring substituted with a methyl group at the ortho position, which influences its reactivity and sterics. Typically, 2-methylphenylmagnesium bromide is used in organic synthesis for the formation of carbon-carbon bonds, allowing for the introduction of the 2-methylphenyl group into various substrates. It is usually prepared by reacting 2-methylbromobenzene with magnesium in an anhydrous ether solvent, such as diethyl ether or tetrahydrofuran, under inert conditions to prevent moisture interference. As a Grignard reagent, it must be handled with care, as it reacts vigorously with water and other protic solvents, releasing hydrocarbons and potentially causing hazardous situations. Proper storage and handling protocols are essential to maintain its stability and reactivity in laboratory settings.

Formula: C₇H₇BrMg

InChI: InChI=1S/C7H7.BrH.Mg/c1-7-5-3-2-4-6-7;;/h2-5H,1H3;1H;/q;;+1/p-1

InChI key: InChIKey=DVXDIGKNJYSMFM-UHFFFAOYSA-M

SMILES: [Mg](Br)C1=C(C)C=CC=C1

Synonyms:

• (2-Methylphenyl)Magnesium(1+) Bromide
• 2-Methylphenylmagnesium bromide
• 2-Tolylmagnesium bromide
• Bromo(2-methylphenyl)magnesium
• Bromo-o-tolylmagnesium
• Magnesium Bromide Methylbenzenide (1:1:1)
• Magnesium, bromo(2-methylphenyl)-
• Magnesium, bromo-o-tolyl-
• Ortho-methylphenylmagnesium bromide
• o-Methylphenylmagnesium bromide
• o-Tolylmagnesium bromide

o-Tolylmagnesium Bromide (ca. 17% in Tetrahydrofuran, ca. 0.9mol/L)

CAS: 932-31-0

Formula: C₇H₇BrMg

Color and Shape: Liquid

Molecular weight: 195.34

Ref: 3B-T1698

2-Tolylmagnesium bromide 0.5M solution in THF

CAS: 932-31-0

2-Tolylmagnesium bromide 0.5M solution in THF

Purity: ≥95%

Molecular weight: 195.34g/mol

Ref: 54-OR320030

2-Tolylmagnesium bromide 2M solution in DEE

CAS: 932-31-0

2-Tolylmagnesium bromide 2M solution in DEE

Purity: ≥95%

Molecular weight: 195.33947g/mol

Ref: 54-OR320031

2-Methylphenylmagnesium bromide 0.5 M in Tetrahydrofuran

CAS: 932-31-0

Formula: C₇H₇BrMg

Color and Shape: Liquid

Molecular weight: 195.342

Ref: 10-F214285

o-Tolylmagnesium Bromide

Controlled Product

CAS: 932-31-0

o-Tolylmagnesium bromide is a reagent for the preparation of chlorides, bromides, iodides, and phosphates. It is used in the Friedel-Crafts reaction to convert alkenes into alkyl halides. The compound is also used as an intermediate in the synthesis of polymers such as polyethylene and polypropylene. o-Tolylmagnesium bromide can be prepared by reacting hydrochloric acid with o-tolylmagnesium chloride. This compound has a nucleophilic attack on the electrophilic carbon atom of the hydrochloric acid molecule, followed by a proton transfer from water to yield hydrobromic acid (HBr). The reaction is selective because the attacking nucleophile can only react at that specific site. X-ray crystal structures have been obtained for three different crystalline forms: monoclinic, orthorhombic, and hexagonal phases. NMR

Purity: Min. 95%

Ref: 3D-FT43107