CAS 932-52-5

5-Aminouracil

Description:

5-Aminouracil is a pyrimidine derivative and an analog of uracil, characterized by the presence of an amino group at the 5-position of the uracil ring. Its molecular formula is C4H4N2O2, and it has a relatively low molecular weight. This compound is typically a white to off-white crystalline solid, soluble in water and various organic solvents, which facilitates its use in biochemical applications. 5-Aminouracil is known for its role in nucleic acid metabolism and has been studied for its potential therapeutic applications, particularly in the context of antiviral and anticancer research. The amino group enhances its reactivity and allows for various chemical modifications, making it a valuable compound in medicinal chemistry. Additionally, it can participate in hydrogen bonding due to the presence of both amino and carbonyl functional groups, influencing its interactions in biological systems. Overall, 5-Aminouracil serves as an important building block in the study of nucleobase analogs and their biological implications.

Formula: C₄H₅N₃O₂

InChI: InChI=1S/C4H5N3O2/c5-2-1-6-4(9)7-3(2)8/h1H,5H2,(H2,6,7,8,9)

InChI key: InChIKey=BISHACNKZIBDFM-UHFFFAOYSA-N

SMILES: O=C1C(N)=CNC(=O)N1

Synonyms:

• 2,4(1H,3H)-Pyrimidinedione, 5-amino-
• 2,4-Dihydroxy-5-aminopyrimidine
• 5-Amino uracil
• 5-Amino-2,4(1H,3H)-pyrimidinedione
• 5-Amino-2,4-dihydroxypyrimidine
• 5-Amino-2,4-pyrimidinediol
• 5-aminopyrimidine-2,4(1H,3H)-dione
• Ai3-50678
• Nsc 22474
• Uracil, 5-amino-
• 5-Aminouracil

5-Aminouracil

CAS: 932-52-5

Formula: C₄H₅N₃O₂

Purity: >98.0%(HPLC)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 127.10

Ref: 3B-A0898

5-Aminouracil, 97%

CAS: 932-52-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₅N₃O₂

Purity: 97%

Color and Shape: Powder, White to cream to yellow to orange to brown

Molecular weight: 127.10

Ref: 02-L04452

5-Aminopyrimidine-2,4(1H,3H)-dione

CAS: 932-52-5

Formula: C₄H₅N₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 127.1014

Ref: IN-DA003MES

5-Aminouracil

CAS: 932-52-5

Formula: C₄H₅N₃O₂

Purity: ≥ 97.0%

Color and Shape: Light beige to brown powder

Molecular weight: 127.10

Ref: 7W-GK2607

5-Aminouracil

CAS: 932-52-5

5-Aminouracil

Purity: 99%

Molecular weight: 127.10g/mol

Ref: 54-OR1011811

5-Aminouracil

CAS: 932-52-5

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Formula: C₄H₅N₃O₂

Purity: Min. 97.5 Area-%

Molecular weight: 127.10 g/mol

Ref: 3D-A-7410

5-Aminouracil

CAS: 932-52-5

5-Aminouracil is a pyrimidine nucleoside that is used in the treatment of cancer, psoriasis and other autoimmune disorders. 5-Aminouracil is a prodrug that undergoes intracellular transformation to become an inhibitor of DNA synthesis. It promotes apoptosis by inhibiting the production of RNA and protein synthesis, leading to cell death. 5-Aminouracil has been shown to be effective against malignant cells in tissue culture as well as various types of cancer cells. A study using hydrogen bonding interactions showed that 5-aminouracil binds to the ribosomal protein L10 and inhibits its function in the polymerase chain reaction (PCR). Molecular docking studies have also shown that this drug can bind with redox potentials in both the active site and ligand binding site of human topoisomerase II alpha, which may lead to inhibition of enzyme activity or cell death.

Formula: C₄H₅N₃O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 127.1 g/mol

Ref: 3D-FA32347

5-Aminopyrimidine-2,4(1H,3H)-dione

CAS: 932-52-5

Formula: C₄H₅N₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 127.103

Ref: 10-F222509