CymitQuimica logo

CAS 93221-48-8

:

(-)-Betaxolol

Description:
(-)-Betaxolol is a selective beta-1 adrenergic antagonist primarily used in the treatment of hypertension and certain types of glaucoma. It is characterized by its ability to selectively block beta-1 receptors in the heart, leading to a decrease in heart rate and myocardial contractility, which helps lower blood pressure. This compound is a chiral molecule, with the (-) designation indicating its specific stereoisomer, which is crucial for its pharmacological activity. (-)-Betaxolol is typically administered orally and is known for its favorable pharmacokinetic profile, including good oral bioavailability and a relatively long half-life. Additionally, it exhibits minimal effects on beta-2 adrenergic receptors, which helps reduce the risk of bronchoconstriction, making it a safer option for patients with respiratory conditions. The substance is also recognized for its ocular hypotensive effects, making it beneficial in managing intraocular pressure in glaucoma patients. Overall, (-)-Betaxolol is an important therapeutic agent with specific applications in cardiovascular and ophthalmic medicine.
Formula:C18H29NO3
InChI:InChI=1S/C18H29NO3/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3/t17-/m0/s1
InChI key:InChIKey=NWIUTZDMDHAVTP-KRWDZBQOSA-N
SMILES:O(C[C@H](CNC(C)C)O)C1=CC=C(CCOCC2CC2)C=C1
Synonyms:
  • (-)-Betaxolol
  • (2S)-1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol
  • (2S)-1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol
  • (S)-(-)-Betaxolol
  • 2-Propanol, 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-, (2S)-
  • 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, (S)-
  • Levobetaxolol [INN]
  • Unii-75O9Xha4Tu
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 1 products.