CAS 933-86-8

1-(Methyl-d3)-2-pyrrolidinone

Description:

1-(Methyl-d3)-2-pyrrolidinone, with the CAS number 933-86-8, is a deuterated derivative of 2-pyrrolidinone, a cyclic amide. This compound features a five-membered ring structure containing a nitrogen atom and a carbonyl group, which contributes to its polar nature and ability to act as a solvent. The presence of deuterium (d3) in the methyl group indicates that it has been isotopically labeled, which can be useful in various analytical applications, including NMR spectroscopy. 1-(Methyl-d3)-2-pyrrolidinone is typically colorless to pale yellow and has a relatively high boiling point, making it suitable for high-temperature applications. It is miscible with water and many organic solvents, enhancing its utility in chemical synthesis and as a solvent for polar compounds. Additionally, this compound is often used in research and industrial applications, particularly in the fields of pharmaceuticals and materials science, due to its ability to dissolve a wide range of substances and its relatively low toxicity.

Formula: C₅H₆D₃NO

InChI: InChI=1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3/i1D3

InChI key: InChIKey=SECXISVLQFMRJM-FIBGUPNXSA-N

SMILES: O=C1N(C([2H])([2H])[2H])CCC1

Synonyms:

• 2-Pyrrolidinone, 1-(methyl-d3)-
• 1-(Methyl-d3)-2-pyrrolidinone

1-Methyl-2-pyrrolidinone-d3

Controlled Product

CAS: 933-86-8

Applications Labelled 1-Methyl-2-pyrrolidinone (M326120). It is a versatile industrial solvent. NMP is currently approved for use only in veterinary pharmaceuticals. The determination of the disposition and metabolism of NMP in the rat will contribute toward understanding the toxicology of this exogenous chemical which man may likely be exposed to in increasing amounts.
References Southwell, D., et al.: J. Pharm. Pharmacol., 33, 3 (1981), Barry, W., et al.: J. Invest. Dermatol., 82, 49 (1984),

Formula: C₅H₆D₃NO

Color and Shape: Neat

Molecular weight: 102.15

Ref: TR-M326122