CAS 93379-54-5

(-)-Atenolol

Description:

(-)-Atenolol is a selective beta-1 adrenergic receptor blocker primarily used in the treatment of hypertension and certain heart conditions. It is a chiral compound, with the (-) designation indicating its specific stereoisomer, which is biologically active. The molecular formula of atenolol is C14H22N2O3S, and it features a sulfonamide group, a hydroxyl group, and an aromatic ring, contributing to its pharmacological properties. This compound is known for its ability to reduce heart rate and myocardial contractility, making it effective in managing conditions such as angina and arrhythmias. Atenolol is typically administered orally and has a moderate bioavailability, with a half-life that allows for once-daily dosing. It is generally well-tolerated, though potential side effects may include fatigue, dizziness, and gastrointestinal disturbances. As with other beta-blockers, caution is advised in patients with asthma or certain cardiovascular conditions due to the risk of bronchoconstriction and bradycardia. Overall, (-)-Atenolol remains a widely used medication in cardiovascular therapy.

Formula: C₁₄H₂₂N₂O₃

InChI: InChI=1/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)/t12-/m0/s1

InChI key: InChIKey=METKIMKYRPQLGS-LBPRGKRZSA-N

SMILES: O(C[C@H](CNC(C)C)O)C1=CC=C(CC(N)=O)C=C1

Synonyms:

• (-)-Atenolol
• (S)-2-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
• 2-[4-[(2S)-2-Hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
• 4-[(2S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
• Benzeneacetamide, 4-[(2S)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
• Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, (S)-
• Esatenolol
• S-Atenolol
• S-(-)-Atenolol
• (S)-Atenolol
• S- AtenololQ: What is
• S- Atenolol Q: What are the applications of
• 2-[4-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethanamide
• 4-[(S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
• S-(-)-4-[2-HYDROXY-3-[(1-METHYLETHYL)AMINO]PROPOXY]BENZENEACETAMIDE
• S- Atenolol Q: What is the CAS Number of
• s-(-)-4-(2-hydroxy-3-isopropylaminopropoxy)phenylacetamide
• (-)-2-[4-[(2S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy] phenyl] acetamide
• Atenolol S-Isomer
• S- Atenolol Q: What is the storage condition of
• S(-)-ATENOLOL >96% ACTIVE ENANTIOMER OF

(S)-(-)-Atenolol

CAS: 93379-54-5

(S)-(-)-Atenolol has beta-adrenergic blocking effects.

Formula: C₁₄H₂₂N₂O₃

Purity: 99.31% - 99.81%

Color and Shape: Solid

Molecular weight: 266.34

Ref: TM-T35833

2-{4-[(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy]phenyl}acetamide

CAS: 93379-54-5

Formula: C₁₄H₂₂N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.3361

Ref: IN-DA003CMV

(S)-(-)-Atenolol

CAS: 93379-54-5

Formula: (CH₃)₂CHNHCH₂CH(OH)CH₂OC₆H₄CH₂CONH₂

Molecular weight: 266.34

Ref: 7W-GL9520

(S)-Atenolol

Controlled Product

CAS: 93379-54-5

Applications Cardioselective β-adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic (class II).
References Caplar, V., et al.: Anal. Profiles Drug Subs., 13, 1 (1984),

Formula: C₁₄H₂₂N₂O₃

Color and Shape: Neat

Molecular weight: 266.34

Ref: TR-A790085

(S)-Atenolol

CAS: 93379-54-5

Formula: C₁₄H₂₂N₂O₃

Molecular weight: 266.33

Ref: ST-EA-CP-A29016