CAS 93413-90-2

N-Desmethylvenlafaxine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 93413-90-2

Color and Shape: Single Solution

Ref: 61-AMP0393.04-01

N-Desmethylvenlafaxine Hydrochloride

CAS: 93413-90-2

Color and Shape: Neat

Ref: 61-FOR0393.04

Venlafaxine Related Compound A (1-(1-(4-Methoxyphenyl)-2-(methylamino)ethyl)cyclohexanol hydrochloride)

CAS: 93413-90-2

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₁₆H₂₅NO₂·HCl

Color and Shape: White Solid

Molecular weight: 263.18853

Ref: 45-1711279

(±)-N-desmethyl Venlafaxine (hydrochloride)

CAS: 93413-90-2

Formula: C₁₆H₂₆ClNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 299.8361

Ref: IN-DA00GW6P

Venlafaxine EP Impurity D HCl (Venlafaxine USP Related Compound A, N-Desmethyl Venlafaxine HCl)

CAS: 93413-90-2

Formula: C₁₆H₂₅NO₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 263.38 36.46

Ref: 4Z-V-035

1-[(1RS)-1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride

Controlled Product

CAS: 93413-90-2

Formula: C₁₆H₂₅NO₂·ClH

Color and Shape: Neat

Molecular weight: 299.84

Ref: 86-MM0393.04

Venlafaxine EP Impurity D-13C-d3 HCl (Venlafaxine USP Related Compound A-13C-d3, N-Desmethyl Venlafaxine-13C-d3 HCl)

CAS: 93413-90-2

Formula: C₁₅₁₃CH₂₂D₃NO₂·HCl

Molecular weight: 267.39 36.46

Ref: 4Z-V-0345

1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride(rac N-Desmethyl Venlafaxine Hydrochloride)

CAS: 93413-90-2

Impurity Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A
Applications 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride (Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A) is a metabolite of Venlafaxine (V120000), which is a selective serotonin noradrenaline reuptake inhibitor, used as an antidepressant.
References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000);

Formula: C₁₆H₂₅NO₂·ClH

Color and Shape: White

Molecular weight: 299.84

Ref: TR-M266250

VENLAFAXINE HCL

CAS: 93413-90-2

Formula: C₁₆H₂₆ClNO₂

Purity: 98%

Molecular weight: 299.84

Ref: 10-F304098

1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride

CAS: 93413-90-2

1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride is a drug product that is not yet approved for use in humans. It is an impurity found in the drug cyclosporine, which is used to treat psoriasis and other skin conditions. 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride has been shown to be inactive in the metabolism studies of rats and dogs. This impurity was detected by HPLC with UV detection at 254 nm, but it did not show any significant absorption at 280 nm. The purity of this compound was determined to be 97% by NMR analysis and HPLC.

Formula: C₁₆H₂₅NO₂·HCl

Purity: Min. 95%

Molecular weight: 299.84 g/mol

Ref: 3D-IM63866

(±)-N-desmethyl Venlafaxine hydrochloride

CAS: 93413-90-2

(±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a minimum effective dose (MED) of 10 mg/kg.

Formula: C₁₆H₂₆ClNO₂

Color and Shape: Solid

Molecular weight: 299.836

Ref: TM-T84941