Rabeprazole-d4 is a deuterated form of rabeprazole, a proton pump inhibitor (PPI) commonly used to treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. The "d4" designation indicates that this compound contains four deuterium atoms, which are isotopes of hydrogen, replacing the regular hydrogen atoms in the molecular structure. This modification is often utilized in research to trace metabolic pathways or to study pharmacokinetics without interference from the non-deuterated form. Rabeprazole-d4 functions by inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to a reduction in gastric acid secretion. Its characteristics include a specific molecular weight and unique spectral properties due to the presence of deuterium, which can be advantageous in analytical techniques such as NMR spectroscopy. As a stable isotopic compound, rabeprazole-d4 is valuable in scientific studies, particularly in understanding drug metabolism and interactions in biological systems.

Rabeprazole-d4

934295-48-4: Rabeprazole-d4 is a deuterated form of rabeprazole, a proton pump inhibitor (PPI) commonly used to treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. The "d4" designation indicates that this compound contains four deuterium atoms, which are isotopes of hydrogen, replacing the regular hydrogen atoms in the molecular structure. This modification is often utilized in research to trace metabolic pathways or to study pharmacokinetics without interference from the non-deuterated form. Rabeprazole-d4 functions by inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to a reduction in gastric acid secretion. Its characteristics include a specific molecular weight and unique spectral properties due to the presence of deuterium, which can be advantageous in analytical techniques such as NMR spectroscopy. As a stable isotopic compound, rabeprazole-d4 is valuable in scientific studies, particularly in understanding drug metabolism and interactions in biological systems.

<p>Applications Rabeprazole-d4 is the labeled analogue of Rabeprazole (R070500), a partially reversible gastric proton pump inhibitor.<br>References Morii, M., and Takeguchi, N.: J. Biol. Chem., 268, 21553 (1993); Yasuda, S., et al.: Int. J. Clin. Pharmacol. Ther., 32, 466 (1994); Cloud, M.L., et al.: Dig. Dis. Sci., 43, 993 (1998)<br></p>

CAS 934295-48-4

Rabeprazole-d4

Rabeprazole-d4

Ref: TR-R070492

Rabeprazole-d4

Ref: IN-DA00GW0D