CAS 93438-65-4

Conotoxin G V

Description:

Conotoxin G V is a peptide derived from the venom of cone snails, specifically from the species Conus geographus. This substance is classified as a neurotoxin and is known for its ability to selectively block certain ion channels, particularly voltage-gated sodium channels. Conotoxin G V exhibits a high degree of specificity and potency, making it a subject of interest in pharmacological research, particularly for its potential applications in pain management and neurological disorders. The structure of this peptide typically includes a series of disulfide bonds that contribute to its stability and biological activity. Its mechanism of action involves the inhibition of neurotransmitter release, which can lead to profound effects on synaptic transmission. Due to its unique properties, Conotoxin G V is studied not only for its potential therapeutic uses but also for its role in understanding the complex interactions of neurotoxins and their targets in the nervous system.

Formula: C₈₈H₁₃₈N₂₆O₄₄

Synonyms:

• 128: PN:US20090175821 PAGE: 404 claimed protein
• Conantokin G
• L-Aspartamide, glycyl-L-a-glutamyl-4-carboxy-L-a-glutamyl-4-carboxy-L-a-glutamyl-L-leucyl-L-glutaminyl-4-carboxy-L-a-glutamyl-L-asparaginyl-L-glutaminyl-4-carboxy-L-a-glutamyl-L-leucyl-L-isoleucyl-L-arginyl-4-carboxy-L-a-glutamyl-L-lysyl-L-seryl-
• (asn-oh17)-conantokin-G

Conantokin G

CAS: 93438-65-4

GluN2B-specific NMDA receptor blocker; IC50=480 nM in neurons, ~300 nM in oocytes; neuroprotective.

Formula: C₈₈H₁₃₈N₂₆O₄₄

Purity: 98%

Color and Shape: White Lyophilised Solid

Molecular weight: 2264.21

Ref: TM-TP2060

Conantokin G trifluoroacetic acid

CAS: 93438-65-4

Conantokin G trifluoroacetic acid is a peptide that is derived from the conantokins. It has been shown to have neuroprotective properties and inhibitory properties. Conantokin G trifluoroacetic acid binds to calcium in neuronal cells, which leads to the inhibition of glutamate-induced neuronal death and brain infarction. The binding of this peptide to calcium also inhibits intracellular signalling pathways, leading to an anti-inflammatory response. In addition, this compound may be a potential therapeutic agent for chronic oral toxicity due to its ability to bind with glutamate receptors and prevent activation.

Formula: C₈₈H₁₃₈N₂₆O₄₄•TFA

Purity: Min. 95%

Molecular weight: 2,264.21 g/mol

Ref: 3D-TDA43865