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CAS 93479-96-0

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Alteconazole

Description:
Alteconazole is an antifungal agent belonging to the class of imidazole derivatives, primarily used in the treatment of fungal infections. Its chemical structure features a 1,2,4-triazole ring, which is characteristic of many antifungal compounds, allowing it to inhibit the synthesis of ergosterol, an essential component of fungal cell membranes. This mechanism disrupts the integrity of the fungal cell, leading to cell death. Alteconazole is typically administered topically and is effective against a range of dermatophytes and yeast infections. The compound is known for its relatively low toxicity profile, making it suitable for use in various formulations, including creams and ointments. In terms of physical properties, Alteconazole is generally a white to off-white solid, with moderate solubility in organic solvents. Its stability and efficacy can be influenced by factors such as pH and temperature, which are important considerations in formulation development. Overall, Alteconazole represents a valuable option in antifungal therapy, particularly for superficial infections.
Formula:C17H12Cl3N3O
InChI:InChI=1/C17H12Cl3N3O/c18-12-3-1-11(2-4-12)17(8-23-10-21-9-22-23)16(24-17)14-6-5-13(19)7-15(14)20/h1-7,9-10,16H,8H2/t16-,17-/m0/s1
Synonyms:
  • Alteconazole [INN]
  • UNII-EA590X615B
  • Alteconazol
  • Alteconazolum
  • cis-1-(2-(4-Chlorphenyl)-3-(2,4-dichlorphenyl)-2,3-epoxypropyl)-1H-1,2,4-triazol
  • 1-{[(2S,3R)-2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole
  • 1-{[(2R,3S)-2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole
  • cis-1-(2-(p-Chlorophenyl)-3-(2,4-dichlorophenyl)-2,3-epoxypropyl)-1H-1,2,4-triazole
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