CAS 93515-00-5

2-Iodomelatonin

Description:

2-Iodomelatonin is a synthetic derivative of melatonin, which is a hormone primarily involved in regulating sleep-wake cycles. This compound features an iodine atom substituted at the 2-position of the indole ring, which alters its biological activity and properties compared to melatonin. It is characterized by its molecular formula, which includes carbon, hydrogen, nitrogen, oxygen, and iodine atoms. 2-Iodomelatonin exhibits potential pharmacological effects, including antioxidant properties and the ability to modulate circadian rhythms. Its structure allows it to interact with melatonin receptors, potentially influencing sleep patterns and neuroprotective mechanisms. The presence of the iodine atom may also enhance its lipophilicity, affecting its bioavailability and distribution in biological systems. As a research chemical, 2-Iodomelatonin is of interest in studies related to sleep disorders, neurodegenerative diseases, and other conditions where melatonin's role is significant. However, further research is necessary to fully understand its efficacy and safety profile in clinical applications.

Formula: C₁₃H₁₅IN₂O₂

InChI: InChI=1S/C13H15IN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17)

InChI key: InChIKey=FJDDSMSDZHURBJ-UHFFFAOYSA-N

SMILES: C(CNC(C)=O)C=1C=2C(NC1I)=CC=C(OC)C2

Synonyms:

• Acetamide, N-(2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl)-
• Acetamide, N-(2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl)-, (3beta)-
• N-(2-(2-Iodo-5-methoxy-1H-indol-3-yl)ethyl)acetamide
• N-Acetyl-2-iodo-5-methoxytryptamine
• 2-Iodomelatonin

2-Iodomelatonin

CAS: 93515-00-5

2-Iodomelatonin

Purity: ≥98%

Molecular weight: 358.17g/mol

Ref: 54-BUP15681

2-Iodomelatonin

CAS: 93515-00-5

2-Iodomelatonin, Ki 28 pM, is an MT1 agonist, >5x selective over MT2, used to map melatonin sites in brain/tissues.

Formula: C₁₃H₁₅IN₂O₂

Purity: 99.7%

Color and Shape: Solid

Molecular weight: 358.17

Ref: TM-T10073