CAS 935658-91-6

1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose

CAS: 935658-91-6

1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose is a per-O-acetylated version of 5-alkynyl-L-fucose, an inhibitor of the cellular fucosylation pathway. 1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose can pass through the eukaryotic cell membrane somewhat better than 5-alkynyl-L-fucose can itself, is deacetylated by cellular esterases and interferes with the biosynthesis of the fucosyl-donor and fucosyltransferase substrate GDP-Fuc, thus reducing fucosylation levels during glycoprotein biosynthesis (Dekkers, 2016).

Formula: C₁₅H₁₈O₉

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 342.3 g/mol

Ref: 3D-MT59558

(3S,4R,5R,6S)-6-Ethynyltetrahydro-2H-pyran-2,3,4,5-tetrayl Tetraacetate

Controlled Product

CAS: 935658-91-6

Formula: C₁₅H₁₈O₉

Color and Shape: Neat

Molecular weight: 342.298

Ref: TR-T207375

6-Alkynyl-L-fucose tetraacetate

CAS: 935658-91-6

1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose is a per-O-acetylated version of 5-alkynyl-L-fucose, an inhibitor of the cellular fucosylation pathway. 1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose can pass through the eukaryotic cell membrane somewhat better than 5-alkynyl-L-fucose can itself, is deacetylated by cellular esterases and interferes with the biosynthesis of the fucosyl-donor and fucosyltransferase substrate GDP-Fuc, thus reducing fucosylation levels during glycoprotein biosynthesis.

Formula: C₁₅H₁₈O₉

Purity: Min. 95%

Molecular weight: 342.3 g/mol

Ref: 3D-CKG-23007-V