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CAS 93572-42-0

:

Escherichia coli lipopolysaccharides

Description:
Escherichia coli lipopolysaccharides (LPS) are complex molecules found in the outer membrane of Gram-negative bacteria, including E. coli. They play a crucial role in the structural integrity of the bacterial cell wall and contribute to the organism's pathogenicity. LPS consists of three main components: lipid A, a core oligosaccharide, and an O-antigen polysaccharide chain. Lipid A is responsible for the endotoxic effects associated with Gram-negative infections, as it can trigger strong immune responses in hosts. The core oligosaccharide connects lipid A to the O-antigen, which varies among different strains of E. coli and is important for serotyping. LPS is known for its ability to induce fever and inflammation, making it a significant factor in septic shock. Additionally, it can activate various immune pathways, including the Toll-like receptor (TLR) signaling pathway. Due to its immunogenic properties, LPS is also studied for its potential applications in vaccine development and as an adjuvant in immunotherapy.
Formula:Unspecified
Synonyms:
  • Lipopolysaccharide E. Coli
  • Lipopolysaccharides, Escherichiacoli
  • Escherichia coli lipopolysaccharide
  • Lipopolysaccharides, Escherichia coli
  • Citopyros
  • Escherichia coli lipopolysaccharides
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Found 2 products.
  • Lipopolysaccharides, Escherichiacoli
    Targetmol
    + Info

    Lipopolysaccharides, Escherichiacoli

    CAS:
    <p>LPS E. coli O55:B5: Gram-negative outer membrane macromolecule with lipid A, core oligosaccharide, and O-antigen.</p>
    Purity:98%
    Color and Shape:Solid

    Ref: TM-T41078

  • Lipopolysaccharides - from Escherichia coli O55:B5
    Biosynth
    + Info

    Lipopolysaccharides - from Escherichia coli O55:B5

    CAS:
    <p>Lipopolysaccharides are a heterogeneous group of molecules that include endotoxins, lipid A, and core oligosaccharide. They are released from the cell wall of gram-negative bacteria as a result of bacterial lysis. Lipopolysaccharides are potent activators of immune cells, inducing the secretion of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). TNF-α is also known to induce the production of other pro-inflammatory cytokines including IL-6, IL-8, IL-10, and IL-12. Lipopolysaccharides have been shown to cause liver damage in animals by increasing plasma alanine aminotransferase levels. This may also be due to their ability to induce the production of malondialdehyde and c-reactive protein.</p>
    Color and Shape:Off-White Powder

    Ref: 3D-OL29171

    500mg
    3,273.00€