CAS 936481-23-1

(2'R)-N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine

Controlled Product

CAS: 936481-23-1

Applications (2'R)-N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is an epimer of N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (D199035), which is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.
References Remillard, S., et. al.: Science, 189, 1002 (1975); Prota, A.E., et. al.: P. Natl. Acad. Sci. USA, 111, 13817 (2014);

Formula: C₃₆H₅₀ClN₃O₁₀S

Color and Shape: White

Molecular weight: 752.31

Ref: TR-D199038