CymitQuimica logo

CAS 936500-94-6

:

Elinogrel

Description:
Elinogrel is a chemical compound classified as a thienopyridine derivative, primarily known for its role as an antiplatelet agent. It functions by inhibiting the P2Y12 receptor on platelets, thereby preventing platelet aggregation and reducing the risk of thrombotic events. This mechanism is particularly beneficial in the management of cardiovascular diseases, including acute coronary syndromes and in patients undergoing percutaneous coronary interventions. Elinogrel is characterized by its oral bioavailability and a relatively rapid onset of action compared to other antiplatelet medications. Its pharmacokinetics involve metabolism primarily through the liver, with active metabolites contributing to its therapeutic effects. The compound has been studied for its potential advantages over traditional therapies, including a more favorable bleeding profile. As with any medication, the use of Elinogrel may be associated with side effects, including bleeding risks, and it is essential for healthcare providers to evaluate the risk-benefit ratio for individual patients. Overall, Elinogrel represents a significant advancement in antiplatelet therapy, with ongoing research to further elucidate its clinical applications.
Formula:C20H15ClFN5O5S2
InChI:InChI=1S/C20H15ClFN5O5S2/c1-23-15-9-14-12(8-13(15)22)18(28)27(20(30)25-14)11-4-2-10(3-5-11)24-19(29)26-34(31,32)17-7-6-16(21)33-17/h2-9,23H,1H3,(H,25,30)(H2,24,26,29)
InChI key:InChIKey=LGSDFTPAICUONK-UHFFFAOYSA-N
SMILES:O=C1C=2C(NC(=O)N1C3=CC=C(NC(NS(=O)(=O)C=4SC(Cl)=CC4)=O)C=C3)=CC(NC)=C(F)C2
Synonyms:
  • N-[4-(6-Fluoro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)phenyl]-N′-[(5-chlorothiophen-2-yl)sulfonyl]urea
  • 2-Thiophenesulfonamide, 5-chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-
  • 5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide
  • PRT 060128
  • Elinogrel
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.