CAS 936500-94-6

Elinogrel

Description:

Elinogrel is a chemical compound classified as a thienopyridine derivative, primarily known for its role as an antiplatelet agent. It functions by inhibiting the P2Y12 receptor on platelets, thereby preventing platelet aggregation and reducing the risk of thrombotic events. This mechanism is particularly beneficial in the management of cardiovascular diseases, including acute coronary syndromes and in patients undergoing percutaneous coronary interventions. Elinogrel is characterized by its oral bioavailability and a relatively rapid onset of action compared to other antiplatelet medications. Its pharmacokinetics involve metabolism primarily through the liver, with active metabolites contributing to its therapeutic effects. The compound has been studied for its potential advantages over traditional therapies, including a more favorable bleeding profile. As with any medication, the use of Elinogrel may be associated with side effects, including bleeding risks, and it is essential for healthcare providers to evaluate the risk-benefit ratio for individual patients. Overall, Elinogrel represents a significant advancement in antiplatelet therapy, with ongoing research to further elucidate its clinical applications.

Formula: C₂₀H₁₅ClFN₅O₅S₂

InChI: InChI=1S/C20H15ClFN5O5S2/c1-23-15-9-14-12(8-13(15)22)18(28)27(20(30)25-14)11-4-2-10(3-5-11)24-19(29)26-34(31,32)17-7-6-16(21)33-17/h2-9,23H,1H3,(H,25,30)(H2,24,26,29)

InChI key: InChIKey=LGSDFTPAICUONK-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC(=O)N1C3=CC=C(NC(NS(=O)(=O)C=4SC(Cl)=CC4)=O)C=C3)=CC(NC)=C(F)C2

Synonyms:

• N-[4-(6-Fluoro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)phenyl]-N′-[(5-chlorothiophen-2-yl)sulfonyl]urea
• 2-Thiophenesulfonamide, 5-chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-
• 5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide
• PRT 060128
• Elinogrel

5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide

CAS: 936500-94-6

Formula: C₂₀H₁₅ClFN₅O₅S₂

Purity: 97%

Molecular weight: 523.9450

Ref: IN-DA00H148

Elinogrel

CAS: 936500-94-6

Elinogrel

Purity: ≥95%

Molecular weight: 523.95g/mol

Ref: 54-BUP12875

Elinogrel

Controlled Product

CAS: 936500-94-6

Formula: C₂₀H₁₅ClFN₅O₅S₂

Color and Shape: Neat

Molecular weight: 523.945

Ref: TR-E508028

Elinogrel

CAS: 936500-94-6

Elinogrel (PRT060128) is a competitive and reversible antagonist of platelet P2Y12 with IC50 of 20 nM and exhibits potent antiplatelet effects.

Formula: C₂₀H₁₅ClFN₅O₅S₂

Purity: 98.78%

Color and Shape: Solid

Molecular weight: 523.95

Ref: TM-T11177