CAS 937174-76-0: GSK 690693

Description: GSK 690693 is a small molecule inhibitor primarily known for its role as a selective inhibitor of the protein kinase AKT (also known as protein kinase B). It is part of a class of compounds that target signaling pathways involved in cell growth, survival, and metabolism, making it of interest in cancer research and therapy. The compound exhibits a specific affinity for the AKT isoforms, which play crucial roles in various cellular processes, including apoptosis and glucose metabolism. GSK 690693 has been studied for its potential therapeutic applications in various malignancies, particularly those characterized by aberrant AKT signaling. In terms of its chemical properties, GSK 690693 is characterized by its molecular structure, which includes specific functional groups that contribute to its biological activity and selectivity. As with many kinase inhibitors, its efficacy and safety profile are subjects of ongoing research, particularly in the context of combination therapies and resistance mechanisms in cancer treatment.

Formula: C₂₁H₂₇N₇O₃

InChI: InChI=1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,22,27)/t13-/m0/s1

InChI key: InChIKey=KGPGFQWBCSZGEL-ZDUSSCGKSA-N

SMILES: OC(C#CC=1N=CC(OCC2CNCCC2)=C3C1N=C(C4=NON=C4N)N3CC)(C)C

Synonyms:

• 3-Butyn-2-ol, 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-
• Gsk 690693
• Gsk690693
• 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol

Gsk 690693

CAS: 937174-76-0

• Purity: 98%
• Molecular weight: 425.48g/mol

GSK-690693

CAS: 937174-76-0

• Purity: ≥98%
• Molecular weight: 425.48g/mol

GSK690693

CAS: 937174-76-0

GSK690693

CAS: 937174-76-0

• Formula: C₂₁H₂₇N₇O₃
• Molecular weight: 425.49

GSK-690693

CAS: 937174-76-0

GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also …

• Formula: C₂₁H₂₇N₇O₃
• Purity: 100% - 98.78%
• Color and Shape: Solid
• Molecular weight: 425.48

GSK690693

CAS: 937174-76-0

Please enquire for more information about GSK690693 including the price, delivery time and more detailed …

• Formula: C₂₁H₂₇N₇O₃
• Purity: Min. 95%
• Molecular weight: 425.48 g/mol