CAS 93780-25-7
:3'-epi-Idoxuridine
Description:
3'-epi-Idoxuridine, with the CAS number 93780-25-7, is a synthetic nucleoside analog of thymidine, primarily studied for its antiviral properties, particularly against herpes simplex virus (HSV). This compound features a modified sugar moiety, which contributes to its unique biological activity. It is characterized by the presence of an iodine atom in its structure, which is integral to its mechanism of action, as it can interfere with viral DNA synthesis. 3'-epi-Idoxuridine exhibits a higher selectivity for viral over host cell enzymes, making it a potential candidate for antiviral therapies. The compound is typically administered in a form that allows for effective cellular uptake, and its efficacy is often evaluated in vitro and in vivo. Additionally, it is important to consider its pharmacokinetics, potential side effects, and resistance patterns when assessing its therapeutic applications. Overall, 3'-epi-Idoxuridine represents a significant area of research in the development of antiviral agents.
Formula:C9H11IN2O5
Synonyms:- 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-iodo-2,4(1H,3H)-pyriMidinedione
- Idoxuridine Impurity 3
- 3'-epi-Idoxuridine
- 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-threo-pentofuranosyl)-5-iodo-
- Idoxuridine 3-Epi Impurity
- 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-iodouracil
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Found 2 products.
3'-epi-idoxuridine
CAS:<p>3'-Epi-idoxuridine is a nucleoside analog that inhibits viral DNA synthesis. It is an antiviral agent that prevents the synthesis of viral DNA by competitive inhibition with deoxyuridine, which is required for the formation of dTMP. 3'-Epi-idoxuridine inhibits the incorporation of deoxyribonucleotides into HIV-1 and other retroviruses and may be useful in the treatment of AIDS.</p>Formula:C9H11IN2O5Purity:Min. 95%Molecular weight:354.1 g/mol
