CAS 938-55-6

6-DMAP

Description:

6-Dimethylaminopurine (6-DMAP) is a chemical compound that belongs to the class of purine derivatives. It is characterized by its dimethylamino group attached to the purine structure, which influences its biological activity. 6-DMAP is primarily known for its role as a potent inhibitor of protein kinases and has been utilized in various biochemical research applications, particularly in studies related to cell signaling and regulation. The compound is often employed in the field of molecular biology, especially in the context of cell cycle studies and as a tool for investigating the mechanisms of action of certain drugs. In terms of physical properties, 6-DMAP is typically a white to off-white crystalline solid, soluble in polar organic solvents. Its molecular structure allows it to interact with various biological targets, making it a valuable compound in pharmacological research. However, safety precautions should be observed when handling 6-DMAP, as with any chemical substance, to mitigate potential health risks.

Formula: C₇H₉N₅

InChI: InChI=1/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-5H,1-2H3

InChI key: InChIKey=BVIAOQMSVZHOJM-UHFFFAOYSA-N

SMILES: N(C)(C)C1=C2C(N=CN2)=NC=N1

Synonyms:

• 1H-Purin-6-amine, N,N-dimethyl-
• 6,6-Dimethyladenine
• 6-(Dimethylamino)-purine
• 6-Dimethylaminopurine
• 6-Dmap
• 9H-Purin-6-amine, N,N-dimethyl-
• Adenine, N,N-dimethyl-
• Adenine, N⁶,N⁶-dimethyl-
• Dimethyladenine
• N,N-Dimethyl-6-aminopurine
• N,N-Dimethyladenine
• N,N-dimethyl-5H-purin-6-amine
• N,N-dimethyl-7H-purin-6-amine
• N,N-dimethyl-9H-purin-6-amine
• N⁶,N⁶-Dimethyladenine
• NSC 401568
• Purine, 6-(dimethylamino)-
• Adenine, N6,N6-dimethyl-
• TIMTEC-BB SBB008765
• N,N-Dimethylpyridin-4-amine
• 4-DIMETHYLAMINOPYRIDINE
• DIMETHYLAMINO PYRIDINE
• DIMETHYLAMINOPYRIDINE, 4-
• 6-Dimethyladenine
• DMAP
• 4-(N,N-DIMETHYLAMINO)-PYRIDINE
• N6,N6-DIMETHYLADENINE
• N,N-DIMETHYL-N-(4-PYRIDINYL)AMINE
• N,N'-DIMETHYL-4-PYRIDINAMINE
• 4DAMPY
• N-(4-PYRIDYL)DIMETHYLAMINE
• 6-Dimethylamino-9H-purine

6-(Dimethylamino)purine

CAS: 938-55-6

Formula: C₇H₉N₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 163.18

Ref: 3B-D3894

N,N-Dimethyl-7H-purin-6-amine

CAS: 938-55-6

Formula: C₇H₉N₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 163.1799

Ref: IN-DA003SKS

6-(Dimethylamino)purine

CAS: 938-55-6

6-(Dimethylamino)purine

Purity: ≥98%

Molecular weight: 163.18g/mol

Ref: 54-BUP17250

6-(Dimethylamino)purine

CAS: 938-55-6

Formula: C₇H₉N₅

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 163.18

Ref: 7W-GL5650

6-(Dimethylamino)purine

CAS: 938-55-6

6-(Dimethylamino)purine

Formula: C₇H₉N₅

Purity: By hplc: 99.52% (Typical Value in Batch COA)

Color and Shape: white to almost white powder

Molecular weight: 163.18g/mol

Ref: 54-BIB1476

6-(Dimethylamino)purine

CAS: 938-55-6

6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor

Formula: C₇H₉N₅

Purity: 99.01% - 99.77%

Color and Shape: Solid

Molecular weight: 163.18

Ref: TM-T7444

6-Dimethylaminopurine

CAS: 938-55-6

Applications A purine antagonist. In the benzodiazepine receptor (BZR) binding assay, it inhibits the binding of 1.5 nM [3H]diazepam at 100uM in rat brains.
References Elion, G.B., et al.: JACS, 74, 411-414 (1952), Kelley, J.L., et al.: J. Med. Chem., 32, 1020-1024 (1989)

Formula: C₇H₉N₅

Color and Shape: Neat

Molecular weight: 163.18

Ref: TR-D461900

6-(Dimethylamino)purine

CAS: 938-55-6

6-(Dimethylamino)purine (6-DAP) is a purine nucleoside that acts as an inhibitor of the transcription factor leukemia inhibitory factor (LIF). 6-DAP binds to the response element in the promoter region of LIF and blocks the binding of LIF to this site. This prevents transcription of LIF, which leads to cell cycle arrest. 6-DAP also has inhibitory effects on skin cells and inhibits the formation of fetal bovine serum protein in a model system. 6-DAP binds to nuclear DNA and alters its structure, which may cause problems with DNA replication or transcription.

Formula: C₇H₉N₅

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 163.18 g/mol

Ref: 3D-FD04709

N,N-Dimethyl-7H-purin-6-amine

CAS: 938-55-6

Formula: C₇H₉N₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 163.184

Ref: 10-F240264