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CAS 93919-41-6

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Sodium 2′-deoxyguanosine 5′-(tetrahydrogen triphosphate) (3:1)

Description:
Sodium 2′-deoxyguanosine 5′-(tetrahydrogen triphosphate) (3:1), commonly referred to as dGTP, is a nucleotide that plays a crucial role in cellular metabolism and biochemistry. It is a derivative of guanosine, featuring a deoxyribose sugar and three phosphate groups, which are essential for energy transfer and signaling in biological systems. The sodium salt form indicates that sodium ions are associated with the molecule, enhancing its solubility in aqueous solutions. dGTP is integral in DNA synthesis, serving as a substrate for DNA polymerases during replication and repair processes. Its structure allows for the formation of hydrogen bonds with complementary bases, ensuring accurate base pairing. Additionally, dGTP is involved in various cellular signaling pathways and can act as a cofactor in enzymatic reactions. The compound is typically stable under physiological conditions but may be sensitive to hydrolysis, particularly in the presence of nucleases. Overall, dGTP is a vital component in the molecular machinery of life, facilitating the storage and transfer of genetic information.
Formula:C10H16N5O13P3·3Na
InChI:InChI=1S/C10H16N5O13P3.3Na/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17);;;/t4-,5+,6+;;;/m0.../s1
InChI key:InChIKey=KQAICEQTDXGYDV-BIHLCPNHSA-N
SMILES:O=C1C2=C(N(C=N2)[C@@H]3O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](O)C3)NC(N)=N1.[Na]
Synonyms:
  • 2'-Deoxyguanosine-5'-Triphosphate Trisodium Salt
  • 2-Deoxyguanosine 5-triphosphoric acid trisodium salt (dGTP)
  • Guanosine 5′-(tetrahydrogen triphosphate), 2′-deoxy-, sodium salt (1:3)
  • Guanosine 5′-(tetrahydrogen triphosphate), 2′-deoxy-, trisodium salt
  • Sodium 2′-deoxyguanosine 5′-(tetrahydrogen triphosphate) (3:1)
  • dGTP,100mM Solution
  • trisodium 2'-deoxy-5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]guanosine
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