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CAS 93942-91-7

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(Ac-Tyr1,D-Arg2)-GRF (1-29) amide (human)

Description:
(Ac-Tyr1,D-Arg2)-GRF (1-29) amide is a synthetic peptide that mimics the structure of the human growth hormone-releasing factor (GRF). This compound is characterized by its specific amino acid sequence, which includes an acetylated tyrosine at the N-terminus and a D-arginine at the second position, enhancing its stability and bioactivity. The peptide consists of 29 amino acids and is typically used in research related to growth hormone regulation and endocrine function. Its amide form contributes to increased resistance to enzymatic degradation, making it more effective in biological applications. The presence of the D-arginine is particularly significant as it can improve receptor binding and biological activity compared to its L-arginine counterpart. Overall, this peptide is of interest in pharmacological studies and potential therapeutic applications related to growth hormone deficiencies and metabolic disorders.
Synonyms:
  • Ac-Tyr-D-Arg-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
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