CAS 93957-53-0

rel-Methyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoate

Description:

Rel-Methyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoate, with CAS number 93957-53-0, is a complex organic compound characterized by its specific stereochemistry and functional groups. It features a heptenoate backbone, which includes a double bond and hydroxyl groups at the 3 and 5 positions, contributing to its reactivity and potential biological activity. The presence of a fluorophenyl group and an indole moiety suggests that this compound may exhibit significant interactions with biological targets, potentially influencing its pharmacological properties. The stereochemistry indicated by the (3R,5S) configuration is crucial for its biological activity, as it can affect how the molecule interacts with enzymes or receptors. Overall, this compound's unique structure may make it of interest in medicinal chemistry, particularly in the development of new therapeutic agents. Further studies would be necessary to elucidate its specific properties and potential applications.

Formula: C₂₅H₂₈FNO₄

InChI: InChI=1/C25H28FNO4/c1-16(2)27-22-7-5-4-6-21(22)25(17-8-10-18(26)11-9-17)23(27)13-12-19(28)14-20(29)15-24(30)31-3/h4-13,16,19-20,28-29H,14-15H2,1-3H3/b13-12+

InChI key: InChIKey=BOCZYIUKFAQNLG-NQHJCFGNNA-N

SMILES: C(=C/[C@@H](C[C@@H](CC(OC)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3

Synonyms:

• (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid methyl ester
• 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, methyl ester, (3R,5S,6E)-rel-
• 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, methyl ester, [R*,S*-(E)]-
• Fluvastatin Methyl Ester
• Luvastatin Methyl Ester
• Methyl (3R,5S,6E)-7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-3,5-Dihydroxy-6-Heptenoate
• methyl (6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
• rel-Methyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoate
• t-Butyl(E)-3,5-dihydroxy-7-[3′-(4″-fluorophenyl)1′-methylethyl-lndoi-2′-yl]-6-heptenoste
• FLUVASTATIN MEHTYL ESTER
• Tert-butyl(E)-3,5-Dihydroxy-7-[3-(4-Fluorophenyl)-1-Methylethyl-Indol-2'-yl] Hept-6-enoate
• R*,S*-(E)]-(±)-7-[3-(4-FLUOROPHENYL)-1-(1-METHYLETHYL)-1H-INDOL-2-YL]-3,5-DIHYDROXY-6-HEPTENOIC ACID TERT BUTYL ESTER (FLUVASTATIN DIOL T-BUTYL ESTER)

Fluvastatin Methyl Ester

Controlled Product

CAS: 93957-53-0

Formula: C₂₅H₂₈FNO₄

Color and Shape: Neat

Molecular weight: 425.49

Ref: 86-MM0676.09

Fluvastatin Methyl Ester

Controlled Product

CAS: 93957-53-0

Applications An intermediate for the selective synthesis of Fluvastatin (F601250).
References Noguchi, N., et al.: Biochim. Biophys. Acta, 1213, 176 (1994), Mitani, H., et al.: Br. J. Pharmacol., 119, 1269 (1996), Yamamoto, A., et al.: Eur. J. Pharm., 361, 143 (1998),

Formula: C₂₅H₂₈FNO₄

Color and Shape: Neat

Molecular weight: 425.49

Ref: TR-F601275

Fluvastatin Methyl Ester

CAS: 93957-53-0

Fluvastatin Methyl Ester is a precursor of Fluvastatin, a blocker of the enzyme HMG-CoA reductase in liver.

Formula: C₂₅H₂₈FNO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 425.49

Ref: TM-T21042