CAS 939791-38-5

Methanesulfonamide, N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-, benzenesulfonate (1:1)

Description:

Methanesulfonamide, N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-, benzenesulfonate (1:1), with CAS number 939791-38-5, is a complex organic compound characterized by its sulfonamide functional group and a multi-ring structure that includes pyrimidine and indole moieties. This compound typically exhibits properties associated with sulfonamides, such as potential antibacterial activity, although its specific biological activity would depend on its molecular interactions and the presence of substituents. The trifluoromethyl group suggests enhanced lipophilicity, which may influence its pharmacokinetic properties. The presence of multiple nitrogen atoms in the structure indicates potential for hydrogen bonding, which can affect solubility and reactivity. Additionally, the benzenesulfonate component may enhance its stability and solubility in various solvents. Overall, this compound's unique structural features contribute to its potential applications in medicinal chemistry and drug development, particularly in targeting specific biological pathways.

Formula: C₂₁H₂₀F₃N₇O₃S·C₆H₆O₃S

InChI: InChI=1S/C21H20F3N7O3S.C6H6O3S/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16;7-10(8,9)6-4-2-1-3-5-6/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30);1-5H,(H,7,8,9)

InChI key: InChIKey=LKLWTLXTOVZFAE-UHFFFAOYSA-N

SMILES: O=C1NC=2C(=CC(NC=3N=C(NCC4=C(N(S(C)(=O)=O)C)N=CC=C4)C(C(F)(F)F)=CN3)=CC2)C1.S(=O)(=O)(O)C1=CC=CC=C1

Synonyms:

• Methanesulfonamide, N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-, benzenesulfonate (1:1)
• PF-562271 PhSO3H salt
• PF-562271 benzenesulfonate
• Pf 00562271

PF-00562271

CAS: 939791-38-5

Formula: C₂₇H₂₆F₃N₇O₆S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 665.6638

Ref: IN-DA00GU5G

Pf562271 Benzene Sulfonate

CAS: 939791-38-5

Pf562271 Benzene Sulfonate

Purity: 97%

Molecular weight: 665.66g/mol

Ref: 54-PC108608

PF-562271 besylate

CAS: 939791-38-5

PF-562271 besylate

Purity: ≥95%

Molecular weight: 665.66g/mol

Ref: 54-BUP12549

PF-562271 besylate

CAS: 939791-38-5

PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.

Formula: C₂₁H₂₀F₃N₇O₃S·C₆H₆O₃S

Purity: 97.65% - 99.01%

Color and Shape: Solid

Molecular weight: 665.66

Ref: TM-T6177