CAS 94-05-3

Ethyl (ethoxymethylene)cyanoacetate

Description:

Ethyl (ethoxymethylene)cyanoacetate, with the CAS number 94-05-3, is an organic compound that belongs to the class of cyanoacetates. It typically appears as a colorless to pale yellow liquid and is known for its distinctive fruity odor. This compound features a cyano group (-CN) and an ethoxy group (-OCH2CH3), contributing to its reactivity and utility in organic synthesis. Ethyl (ethoxymethylene)cyanoacetate is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, owing to its ability to undergo nucleophilic reactions. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water. The compound is sensitive to moisture and should be handled with care to avoid hydrolysis. Safety precautions are necessary when working with this substance, as it may pose health risks if inhaled or ingested. Proper storage in a cool, dry place, away from incompatible materials, is essential to maintain its stability and efficacy in chemical reactions.

Formula: C₈H₁₁NO₃

InChI: InChI=1/C8H11NO3/c1-3-11-6-7(5-9)8(10)12-4-2/h6H,3-4H2,1-2H3/b7-6+

InChI key: InChIKey=KTMGNAIGXYODKQ-UHFFFAOYSA-N

SMILES: C(C(OCC)=O)(=COCC)C#N

Synonyms:

• 2-(Ethoxymethylene)-2-cyanoacetic acid ethyl ester
• 2-Cyano-3-ethoxy-2-propenoic acid ethyl ester
• 2-Cyano-3-ethoxyacrylic acid ethyl ester
• 2-Propenoic acid, 2-cyano-3-ethoxy-, ethyl ester
• Acrylic acid, 2-cyano-3-ethoxy-, ethyl ester
• Ethyl 2-(ethoxymethylene)-2-cyanoacetate
• Ethyl 2-cyano-2-(ethoxymethylene)acetate
• Ethyl 2-cyano-3-(ethyloxy)-2-propenoate
• Ethyl 2-cyano-3-ethoxy-2-propenoate
• Ethyl 2-cyano-3-ethoxyacrylate
• Ethyl 2-cyano-3-ethoxypropenoate
• Ethyl 2-ethoxymethylidenecyanoacetate
• Ethyl 3-ethoxy-2-cyanoacrylate
• Ethyl cyano(ethoxymethylene)acetate
• Ethyl cyano(ethoxymethylidene)acetate
• Ethyl ethoxymethylenecyanoacetate
• Ethyl α-(ethoxymethylene)-α-cyanoacetate
• NSC 27797
• NSC 31579
• NSC 62026
• ethyl (2E)-2-cyano-3-ethoxyprop-2-enoate
• ethyl (2Z)-2-cyano-3-ethoxyprop-2-enoate
• Ethyl (ethoxymethylene)cyanoacetate
• ETHOXY METHYLENE CYANOACETIC ACID ETHYL ESTER
• 2-Ethoxymethylenecyanoacetic acid ethyl ester
• Ethyl-2-cyan-3-ethoxyacrylat
• Ethoxyl Methylene Cyanoacetic Ethyl
• EMCAE
• Ethyl (E)-2-cyano-3-ethoxyprop-2-enoate
• Ethyl (2E)-2-cyano-3-ethoxy-2-propenoate
• 2-cyano-3-ethoxy-2-propenoicaciethylester
• 2-Propenoicacid,2-cyano-3-ethoxy-,ethylester
• Ethyl alpha-(ethoxymethylene)-alpha-cyanoacetate

Ethyl 2-(Ethoxymethylene)-2-cyanoacetate

CAS: 94-05-3

Formula: C₈H₁₁NO₃

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 169.18

Ref: 3B-E0341

Ethyl (ethoxymethylene)cyanoacetate, 98%

CAS: 94-05-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₁₁NO₃

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder or fused solid or flakes, White to pale cream to cream to yellow to brown

Molecular weight: 169.18

Ref: 02-A12366

Ethyl (ethoxymethylene)cyanoacetate

CAS: 94-05-3

Formula: C₈H₁₁NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 169.1778

Ref: IN-DA0034TP

Ethyl 2-cyano-3-ethoxyacrylate

CAS: 94-05-3

Ethyl 2-cyano-3-ethoxyacrylate

Formula: C₈H₁₁NO₃

Purity: 98%

Color and Shape: pale yellow flakes

Molecular weight: 169.18g/mol

Ref: 54-OR22372

Ethyl (ethoxymethylene)cyanoacetate

CAS: 94-05-3

Formula: C₈H₁₁NO₃

Purity: 95%

Color and Shape: Solid, Crystalline

Molecular weight: 169.18

Ref: 10-F078621

Ethyl Cyano(ethoxymethylene)acetate-13C3

Controlled Product

CAS: 94-05-3

Applications Isotope labelled analog of Ethyl Cyano(ethoxymethylene)acetate, an intermediate in the synthesis of anti-inflammatory agents with gastroprotective effect in rats.
References Karoui, A., et al.: Med. Chem. Res., 23, 1591 (2014);

Formula: C₃C₅H₁₁NO₃

Color and Shape: Neat

Molecular weight: 172.156

Ref: TR-E907512

Ethyl Cyano(ethoxymethylene)acetate

Controlled Product

CAS: 94-05-3

Applications Ethyl Cyano(ethoxymethylene)acetate is an intermediate in the synthesis of anti-inflammatory agents with gastroprotective effect in rats.
References Karoui, A., et al.: Med. Chem. Res., 23, 1591 (2014);

Formula: C₈H₁₁NO₃

Color and Shape: Neat

Molecular weight: 169.18

Ref: TR-E907510

Ethyl (ethoxymethylene) cyanoacetate

CAS: 94-05-3

Ethyl (Ethoxymethylene) cyanoacetate is a chemical compound that belongs to the family of aldehyde compounds. It is a colorless liquid at room temperature, with an odor similar to that of acetic acid. The compound has been used in the synthesis of epidermal growth factor and diazonium salts. It has also been used in the production of anti-cancer drugs such as malonic acid, which inhibits tumor growth by inhibiting protein synthesis. Ethyl (Ethoxymethylene) cyanoacetate reacts with quinoline derivatives to form carbon disulphide, which can be used as an antimicrobial agent and insecticide.

Formula: C₈H₁₁NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 169.18 g/mol

Ref: 3D-FE31152